Scribe Therapeutics is seeking a highly creative, passionate, and motivated individual to join us in our quest to develop the next generation of CRISPR-based therapeutics. The current role is for a Research Associate on the Therapeutic Discovery team to  help execute our in vivo experiments, which are critical to our efforts to develop therapeutic strategies to address the underlying cause of disease. This role will require expertise in basic rodent handling and procedures, or willingness to learn. 

About Scribe:

Scribe uses holistic molecular engineering to design, evolve, build and apply exclusive CRISPR technologies with enhanced therapeutic attributes for in vivo use. The company’s first technology, X-Editing (XE) molecules, are highly engineered CRISPR enzymes that provide combined aspects of greater efficacy, specificity and deliverability than currently available CRISPR genome editing technology. While Scribe’s engineering core continues to evolve and expand, the company is simultaneously addressing diseases of significant unmet need— neurodegenerative disorders.  

Key Responsibilities:

  • Work closely with a core team to creatively design, rapidly build, and efficiently screen therapeutic strategies and constructs in in vivo mouse models.
  • Learn and execute critical in vivo procedures in rodents, tissue processing, and analysis.
  • Aid the vivarium team in maintaining and managing the scale up of the vivarium
  • Help the team design and execute hypothesis-driven and properly controlled studies, analyze data with rigorous statistics, and write up publication quality reports. 
  • Effectively collaborate with members within a fully integrated team to facilitate execution on projects within established timelines.
  • Effectively analyze and present critical in vivo data, and communicate research plans and timelines to the core team.

Required Skills and Background:

  • A BS/BA in Bioengineering, Cell or Molecular Biology, Synthetic Biology, or related discipline. 
  • 2+ years wet lab research experience required.
  • A strong work ethic, a steadfast commitment to discovery research and a documented ability to initiate, drive and complete research projects, as evidenced by a strong publication record.
  • Excellent interpersonal skills and ability to work efficiently and productively in a dynamic, scientifically rigorous, and fast-paced environment.

Preferred Skills and Background:

  • Post graduate studies or pharmaceutical industry experience are a plus.
  • Experience working in a vivarium and rodent handling.
  • Experience with CRISPR-Cas gene editing systems and delivery technology desired.

 

We are committed to creating a diverse environment and are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

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