Caribou is a leading clinical-stage CRISPR genome-editing biopharmaceutical company founded by pioneers in this field. Leveraging our proprietary technologies, we are developing genome-edited, off-the-shelf immune cell therapies for the treatment of patients with devastating human diseases, including cancer. We believe that cell therapies are critical now and for the future of cancer therapeutics, and that advanced genome editing is necessary to develop sophisticated cell therapies to treat a variety of malignancies. We are developing a pipeline of wholly-owned, genome-edited, off-the-shelf CAR-T and CAR-NK cell therapy product candidates for a range of tumor types. Caribou’s headquarters are in Berkeley, California.

Members of the Caribou herd open their minds to new ideas and welcome diverse perspectives. We proudly assert that teams do their best work when their members are personally engaged, their ideas are taken seriously, their contributions are recognized, and their needs are met. 

As a result of exciting developments both with Caribou’s internal pipeline programs and with the addition of a significant external partnership, we have multiple early-stage projects focused on the preclinical discovery and development of CAR-T cell therapy candidates.
We are seeking a Scientist/Senior Scientist to join our Technology Development group. Working in a collaborative environment, you will work to advance and develop novel technologies to enhance the cytotoxicity, proliferation, and persistence of Caribou’s cell therapy products. This is an opportunity for a talented scientist to drive creative discovery and Caribou’s next-generation cell therapy programs.

Responsibilities include:

  • Working with a matrixed team to develop and advance preclinical allogeneic CAR-T cell programs targeting liquid and/or solid tumors
  • Designing, coordinating, executing, and analyzing in vitro and in vivo experiments
  • Thinking creatively, proposing, and implementing innovative cell engineering approaches to expand Caribou’s preclinical pipeline and intellectual property
  • Communicating results clearly and concisely internally and externally
  • Keeping accurate records of experiments and results
  • Mentoring and supporting team members

Qualifications:

  • PhD in cell biology, molecular biology, immunology, or a closely related field
  • Minimum 3 years of relevant postdoctoral experience (academic or industry)
  • Hands-on proficiency in Genome editing, primary cell isolation mammalian cell culture, and developing and performing cell based assays (such as cell activation, proliferation, cytotoxicity and phenotype characterization)
  • Proficiency in a broad range of molecular genetics and cell biology techniques
  • Experience in planning and executing in vitro functional assays
  • Proven track record of problem solving and the ability to adapt and integrate new technologies into existing projects
  • Highly organized with excellent communication and critical thinking skills. Self-motivated with a strong collaborative mindset
  • Ability to develop and mentor a team of researchers
  • Comfort in a fast-paced environment and ability to adjust workload based upon changing priorities

Nice-to-haves:

  • Prior experience with cell therapies or other biologics
  • Experience with Next-Generation Sequencing (NGS) platforms
  • Experience in multi-parameter flow cytometry and data analysis
  • Familiarity with immune cell signaling pathways governing immune response, proliferation, differentiation, and metabolism
  • Experience designing and performing genetic engineering on cultured mammalian cells
  • Work in pharmaceutical or biotechnology company focused on immuno-oncology
  • Understanding of regulatory guidelines for cell therapies
  • First author publications in related discipline

Caribou compensation and benefits include:

  • Comprehensive compensation package, which includes stock options and an employee stock purchase program for all employees
  • Generous paid vacation time, in addition to company-observed holidays and floating holidays
  • Excellent medical, dental, and vision insurance
  • 401(k) retirement savings plan, which includes matching employer contributions
  • Tuition reimbursement program

Caribou is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws. Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. 

Caribou requires employees to be fully vaccinated, including a booster shot, against COVID-19 unless they have an approved medical or religious accommodation. Proof of such vaccination will be required as part of the hiring process.

For more information about Caribou, visit www.cariboubio.com and follow the company @CaribouBio.

Apply for this Job

* Required
  
  


Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Caribou Biosciences, Inc.’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.


Form CC-305

OMB Control Number 1250-0005

Expires 05/31/2023

Voluntary Self-Identification of Disability

Why are you being asked to complete this form?

We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years.

Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:

  • Autism
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
  • Blind or low vision
  • Cancer
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or hard of hearing
  • Depression or anxiety
  • Diabetes
  • Epilepsy
  • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
  • Intellectual disability
  • Missing limbs or partially missing limbs
  • Nervous system condition for example, migraine headaches, Parkinson’s disease, or Multiple sclerosis (MS)
  • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression

1Section 503 of the Rehabilitation Act of 1973, as amended. For more information about this form or the equal employment obligations of Federal contractors, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.