Caribou Biosciences is a leading clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. Our next-generation genome-editing technology enables superior precision to develop cell therapies that are armored to potentially improve antitumor activity. We believe the future of cell therapy is off-the-shelf, and we are advancing our pipeline of off-the-shelf, or allogeneic, cell therapies from our CAR-T and CAR-NK platforms as readily available treatments for patients with hematologic malignancies and solid tumors.

Members of the Caribou herd open their minds to new ideas and welcome diverse perspectives. We proudly assert that teams do their best work when their members are personally engaged, their ideas are taken seriously, and contributions are recognized. Members of the herd work from our headquarters in Berkeley, California, hybrid, or remotely.

Caribou is seeking an experienced, forward-thinking, and culture-driven Senior Director of Human Resources to join our growing organization.  Reporting to the Chief People Officer, the main responsibilities of this role will be to build and lead the Talent Acquisition function, drive culture engagement initiatives, and act as a HR Business Partner, providing counsel, coaching, and support to assigned departments. This position requires excellent strategic and operational human resources leadership, strong organizational development experience, business acumen, strategic and analytical thinking, and the ability to influence, motivate, and communicate effectively with individuals at every level of the company. This role will be hybrid with the expectation to be on-site on a regular basis.

Key responsibilities include:

 HR Business Partner:

  • Collaborate with senior leaders to understand their business goals and objectives
  • Partner with CPO and leadership to identify strategies that support the desired organizational culture across Caribou while also connecting to specific needs of individual functional areas
  • Provide strategic HR guidance and support to ensure alignment between HR initiatives and departmental goals
  • Identify opportunities for organizational improvement and implement initiatives to enhance efficiency and employee engagement
  • Educate, coach, and partner with managers in all issues regarding people management, HR practices, policy, employment law, employee relations, change and performance management, and employee development
  • Partner with leaders and HR on performance management including the facilitation of calibration meetings, compensation support, promotions, and the annual compensation year-end process
  • Partner with hiring managers on recruitment efforts
  • Conduct exit interviews and provide insight/data on an ongoing basis
  • May provide guidance and input on organizational design, workforce planning, and succession planning

Talent Acquisition Leadership:

  • Develop and implement a comprehensive talent acquisition strategy aligned with organizational goals
  • Develop and manage the end-to-end recruitment process, leveraging technology and best practices to improve efficiency and candidate experience
  • Collaborate with hiring managers to understand staffing needs and implement effective recruitment plans
  • Manage external vendors and oversee the various channels of recruiting, including job boards, social media, and industry networking
  • Stay abreast of industry trends and best practices to enhance the organization's competitive position in talent acquisition
  • Establish and monitor key performance indicators (KPIs) to measure the effectiveness of the talent acquisition function

Strategic HR Planning:

  • Contribute to the development and execution of overall HR strategies that support organizational growth and objectives
  • Work with CPO to assess and address the organization's current and future HR needs
  • Partner with CPO to implement effective HR policies and practices that will support the strategic growth of the organization
  • Participate and collaborate with HR team in the continual development of specific programs and initiatives in the areas of performance management, recognition, career development, organizational design, talent development, and employee engagement
  • Work in partnership with CPO on projects related to employee engagement, culture, and DEI
  • Perform other duties as necessary and assigned

Education & Experience:

  • Bachelor’s degree or equivalent experience
  • Requires 15+ years of experience in progressive HR management and/or a business partner role
  • Experience and familiarity with talent acquisition best practices
  • Life Sciences industry experience preferred


  • Strategic thinker with the ability to align HR initiatives with business goals
  • Demonstrated ability to drive organizational change and foster a positive work culture
  • Proven successful track record and knowledge in organizational and employee development, performance management, employee relations, and change management
  • Adept at anticipating emerging human resources issues and designing and implementing strategies and tactics to address them
  • Strong understanding of industry trends and talent market dynamics
  • Familiarity with applicant tracking systems and other recruitment technologies
  • Self-driven and ability to roll up sleeves
  • Effective interpersonal skills to collaborate effectively and build strong relationships
  • Ability to work and communicate with employees at many levels across diverse cultures
  • Exceptional written and verbal communication skills; proven experience articulating strategy-related concepts to all audiences
  • Experience with a HRIS, Microsoft Suite tools (including Outlook, PowerPoint, Word, and Excel)
  • Excellent skills in developing and presenting effective presentations
  • Extensive knowledge of Federal, California, other state and local legal regulations related to employment and HR policies

Caribou compensation and benefits include:

  • Comprehensive compensation package, which includes competitive salary, bonus, and equity for all employees
  • Salary Range: $250,000 to $280,000. This represents the present low and high end of the Company’s pay range for this position. Actual pay will vary based on various factors, including but not limited to location, skill, experience, and performance.
  • Generous paid vacation time, in addition to company-observed holidays and floating holidays
  • Excellent medical, dental, and vision insurance
  • 401(k) retirement savings plan, which includes matching employer contributions
  • Employee stock purchase plan (ESPP)
  • Tuition reimbursement program

The benefits and stock purchase described above are subject to the terms and conditions of any governing plans, policies, practices, agreements, or other materials or documents as in effect from time to time, including but not limited to terms and conditions regarding eligibility.

Caribou is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws.

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

For more information about Caribou, visit and follow the company @CaribouBio

Apply for this Job

* Required
resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Caribou Biosciences, Inc.’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Our system has flagged this application as potentially being associated with bot traffic. Please turn off any VPNs, clear your browser cache and cookies, or try submitting your application in a different browser. If this issue persists, please reach out to our support team via our help center.
Please complete the reCAPTCHA above.