About Watershed

Our vision is to become the leading biocomputing platform. The future of biology is in big data analysis, and we are on a mission to accelerate digital drug discovery with the Watershed platform. Watershed enables scientists to conduct all essential analysis — from lab data to plot — with a single software platform. 

We have attracted some of the best bioinformatics, engineering, and commercial talent, and we are growing! Join a team that’s intellectually curious with a bias for action, headquartered in Cambridge, Massachusetts, composed of people who have come together to enable outcomes while empowering the research of all those committed to changing lives — all while bringing transformational change to a $40 billion industry.


Infrastructure Engineers at Watershed engineer infrastructure to meet the high-performance computing needs of modern biology. Designing systems that keep pace with the explosive growth in the kinds and size of biological data, you will work in a containerized environment where our biocomputing platform and analyses run at scale. You will be tasked with engineering a new cloud experience while enabling our technology evolution in a disciplined way.


  • Build, manage, and deploy an enterprise infrastructure. 
  • Research new technologies and solutions, implement them or build better
  • Be the connection between systems and software
  • Monitor system performance and manage capacity.
  • Fix and analyze technical incidents, solve ad hoc technical problems.


  • Experience composing infrastructure-as-code for a modern environment
  • Demonstrate a software developer mindset, building tools when necessary
  • Knowledge of virtualization, networking, and Linux internals
  • Ability to clearly communicate your thoughts, ask the right questions, and defend your views
  • Responsibility and ownership over your domain


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