VitroLabs is a venture-backed biotechnology startup working towards a world where science is used responsibly to provide positive impact for business, the planet, and all living things. By harnessing novel applications of science and technology, we've developed a process to grow real leather that is cruelty-free and better for the environment.
About the role: Reporting to the Downstream Lead, the Downstream Process Development Engineer, will work with upstream process development, analytical development, and manufacturing to establish critical process parameters for cell production.
You will to work to achieve process efficiency and prevent cell loss. To do this, you will conduct experiments and interpret experimental results to help establish the process for volume reduction of mammalian cell harvest coming out of the bioreactor.
You are an innovation enthusiast and have experience with cellular downstream processing equipment operations, mammalian cell culture, and bioreactor operation. You execute projects from start-to-finish, understand chemical process calculations, and analyze experimental data. You are excited to join a startup company where you can make a big impact.
Achieve large-scale, high-viability cell harvests for tissue production by testing the ranges of critical process parameters for downstream process equipment
Establish robust and scalable downstream processes by performing experiments to optimize process parameters such as flow rates, cell concentrations, centrifugal speeds, cell cryobuffer formulation, and bag filling
Produce and analyze meaningful process data by using Process Analytical Techniques (PAT) to monitor and control downstream operations
Work with the Upstream Processing, Tissue Engineering, Technical Operations and Pilot Manufacturing teams to ensure seamless process integration
Support technology transfer of the downstream process to manufacturing
Communicate with vendors, contractors, and other outside parties to coordinate trainings on and installation of new equipment
Acquire new skills and integrate new technologies
Qualifications & Skills:
Experience concentrating cells from large volumes (many liters) of cell culture media
Understanding of downstream processing steps and how they integrate with upstream processing
Knowledge of Process analytical techniques (PAT)
Hands-on operational knowledge of large-scale downstream unit operations.
Mammalian cell culture experience at large-scale
Experience performing process calculations for mass transfer, mixing and heat transfer
$80,000-95,000 annually, depending on experience
We offer great benefits (health, vision, and dental insurance) and challenging, impactful work. Join our growing team, work with smart and dedicated people, and help develop cutting-edge technologies that will positively impact the world.
The above statements are intended to describe the general nature and level of work being performed by incumbents assigned to this job. This is not intended to be an exhaustive list of all the functions, responsibilities, duties and skills required for the position, and VitroLabs Inc retains the discretion to modify functions, responsibilities, duties and skills at any time, including modifying the time devoted to such activities, deleting activities and assigning other activities.
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
VitroLabs Inc is an equal opportunity employer committed to providing employment opportunities without regard to race, color, sex (including gender identity, sexual orientation, and pregnancy), age, national origin, religion, veteran status, disability, genetic information, or any other protected status in accordance with applicable law.