Vesalius Therapeutics is seeking a Director of Computational Biology to join our effort to reveal biological mechanisms of health and disease. You will report to the VP, Informatics & Data Science and lead the design and analysis of innovative high-throughput experiments that will generate therapeutic hypotheses. You will join an interdisciplinary team with statistical geneticists, biomedical informaticists, machine learning researchers, and wet-lab biologists to support the discovery of novel therapeutic targets.

What You’ll Do:

  • Lead cross-functional, matrixed project teams responsible for generating and testing hypotheses about complex disease processes by setting strategy, goals, and deliverables in collaboration with leaders in Discovery Biology
  • Provide in-depth technical expertise and leadership in applied statistics/machine learning in the context of genomics/proteomics/metabolomics
  • Lead internal efforts to develop innovative new computational methods, and corresponding innovative experimental designs, to address the problem of discovering the mechanistic basis of complex diseases
  • Champion the role of computational biology in driving our discovery platform by building a highly skilled, dynamic team

What You’ll Bring:

  • PhD in Bioinformatics, Biostatistics, Computer Science, Computational Biology, Genetics, Mathematics, Physics, Statistics or other related discipline
  • 7+ years of industry experience working with complex biological data sets
  • Demonstrated knowledge and experience in applied statistics/machine learning, experimental design, and rigorous analysis of experimental data in the context of genomics at bulk and single cell resolution
  • Demonstrated experience leading cross-functional teams of highly skilled scientists to deliver biological insights in a fast-paced environment

What We’ll Offer You:

  • Comprehensive, competitive healthcare (PPO) and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, three weeks’ paid time off with additional holidays, 401k retirement plan, disability and life insurance, and commuter benefits
  • A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team
  • Participation in projects that could redefine treatment of common illnesses
  • Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things
  • Daily on-site snacks, all the coffee you need, as well as weekly catered lunches

Who We Are:

Vesalius is revolutionizing the way common illnesses are understood and treated. Vesalius's DIAMOND™ technology platform allows the company to see through disease complexity to more fully understand the drivers of common illnesses, enabling a far more effective and efficient approach to drug development. Vesalius's platform begins and ends with patients. It elegantly combines human data, genetics and genomics information, artificial intelligence and machine learning, and proprietary experimental models to redefine how we think about and treat common illnesses. Vesalius was founded in 2019 in Flagship Labs, Flagship Pioneering's innovation foundry. For more information visit, or follow us on Twitter and LinkedIn.


Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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