Twist is looking for a Senior Bioinformatics Scientist to join our dynamic R&D Bioinformatics team. As a member of the team you will be working with experimental scientists, data scientists and software engineers on turning novel scientific ideas into best in-class synthetic biology and next-generation sequencing applications. You will lead computational projects, design experiments, perform analyses, build tools, and guide/mentor other members of the team.  Ideally you will have strong domain knowledge in genomics, extensive experience with next-generation sequencing (NGS) and be a collaborative, creative problem solver. Excellent communication skills and experience mentoring and leading other staff are a must.

Responsibilities:

  • Be the liaison between the computational and wet-lab R&D teams to ensure smooth collaboration by setting reasonable expectations and negotiating deliverables and timelines
  • Collaborate with bench scientists to provide computational support in all phases of R&D work; guide wet- and dry-lab scientists in the design and execution of experiments and analysis
  • Provide leadership to the team, help shape the bioinformatics research roadmap
  • Contribute to expanding and improving Twist’s core applications such as target enrichment and panel design 
  • Develop novel bioinformatics solutions for various synthetic biology applications
  • Work closely with the Bioinformatics Software Engineering team to ensure successful transition of project from the R&D to production

Required skills and experience:

  • 5+ years of industry experience, preferably in an R&D environment
  • Experience working with bench scientists on experimental design and on translating biological questions into quantitative ones
  • Proven ability to develop custom algorithms (python) for DNA-based applications
  • Broad experience with NGS technologies (for example: Illumina, PacBio, Nanopore, etc), applications (genotyping, viral, metagenomics, RNA-seq, methylation, single-cell, etc.) and data analysis
  • Strong communication skills
  • Prior experience leading projects and people
  • Ph.D. in Bioinformatics, Computational Biology, Genomics or similar discipline

 Preferred:

  • Experience with Target Enrichment and Panel Design
  • Understanding of good software engineering practices and tools (source control, documentation, code reviews, coding standards, etc)

 

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

San Francisco applicants: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

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