Totus Medicines, an innovative therapeutic drug discovery biotech, is just emerging from stealth. With a $40M Series A, Totus is poised to revolutionize drug discovery. For the first time, Totus is enabling genome-scale drug discovery to allow the identification of precision medicines for hard-to-drug targets. At its core, Totus is a chemical biology company. Totus’ novel proprietary platform allows screening at a rate more than 100,000 times faster than competitive technologies. Totus has pioneered the development of selective medicines for patients with genetically defined cancers and plans for its first program to enter Phase I by end of 2022. Totus also plans to expand their platform to create therapeutics targeted at neurodegeneration, infectious diseases, and others. We are searching for talented, passionate, high-energy candidates to join our growing team.


  • Serve as a program manager for one or more drug development programs, providing coordination and cross-functional communication to enable teams to meet their goals
  • Work with team members to compile high-quality, detailed, integrated cross-functional program plans, manage program activities, timelines, and resources
  • Partner with the scientific lead to facilitate decision making and resolve conflicts; proactively identify key risks, timeline and resource constraints, and develop mitigation plans
  • Effectively communicate program strategy, status, critical path activity timing, resource requirements, and related issues and/or risks as appropriate
  • Effectively lead and manage team meetings by developing agendas, defining and communicating meeting objectives, capturing and disseminating meeting outcomes/information/minutes/action items, and following up on action items
  • Work closely with finance team to support program budget tracking and facilitate approval of changes that arise throughout the year due to changing conditions/plans within the program


  • Bachelor’s degree in science, business or equivalent
  • Experience coordinating assembly of IND submission
  • 6+ years of relevant biotech and/or pharmaceutical industry program management experience, with broad knowledge across all facets of drug development
  • Self-directed, accomplishment-driven individual with a strong sense of passion and urgency who can work both independently and in a cross-functional team environment
  • Strong scientific background and knowledge of the drug development process
  • Close attention to details, innovative problem solving and excellent organizational skills
  • Strong interpersonal skills with the ability to motivate others, to influence without authority, to negotiate for conflict resolution, and to forge consensus between competing points of view
  • Demonstrated success with handling multiple projects and able to handle complexity and prioritize effectively
  • Experience with small molecules a plus, but not required

What We Offer

  • A knowledgeable, high-achieving, experienced and fun team

  • A diverse work atmosphere

  • The chance to be part of a growing startup and the next success story

  • The opportunity to shape our company culture

  • Constant learning and dynamic challenges to help you grow and be the best version of yourself

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