Tome Biosciences is the programmable gene insertion company. Using CRISPR, our technologies allow us to insert any genetic sequence of any size at any location into any genome. We are writing the final chapter in genomic medicines, delivering cures to patients through cell and genome engineering.

Genomics-Screening, RA/SRA

At Tome, we are developing the next generation of programmable gene insertion technology. We are building an exceptional team and a work environment that is diverse, innovative, rewarding, and fun. We have an opportunity to re-write the patient story, and together, we are writing a new chapter in genomic medicines.

 

Our Genomics Team is growing! Reporting to the Screening Director, we are seeking a Research Associate/Scientist to join our organization. This position will be responsible for and contribute to screening for candidate components of our genome medicine. This position will play a critical role in improving our technology and determining what will eventually get into patients.

Key Responsibilities

  • Work with scientific lead to design and implement screenings to optimize programmable gene insertion in different cell types
  • Perform DNA/RNA transfections and viral transductions
  • Quantify genome editing events using various molecular assays
  • Data analysis, figure generation and reporting of results within a timely manner
  • Maintain a clean and organized laboratory space
  • Present findings at small forums and R&D meetings
  • Maintain a thorough and detailed electronic lab notebook

 

Qualifications

  • BS/MS in cell biology, molecular biology or related fields is required with 2+ years of lab experience in industry or academia
  • Have a good understanding of CRISPR technology and hands on experience is preferred
  • Experience in mammalian cell tissue culture, DNA/RNA transfection, bacterial culture, recombinant DNA cloning techniques, Primer design and PCR, Gel electrophoresis, Nucleic acid extraction and purification, (Experience with microscopy a plus)
  • High throughput screening experience with automation is preferred
  • NGS library prep, cell line generation using lentivirus, immunostaining and flowcytometry experience is a plus
  • Must be able to prioritize and manage a high volume, demanding, fast-paced environment
  • Must be organized, self-motivated, proactive, works well under pressure and deadlines, detail oriented
  • Enthusiasm for learning new skills and taking on new responsibilities

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