Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts



Reporting to the General Counsel, the Director of Intellectual Property will help to structure, build and oversee Tango’s intellectual property portfolio through the planning, establishment and implementation of the patent and intellectual property strategy. Specifically, you will lead all IP initiatives in connection with Tango’s growing pre-clinical pipeline and manage all facets of IP through the various stages of product development: discovery, pre-clinical, clinical trials, regulatory approval, and commercialization, as well as product life cycle management. In addition, the role will include defense of third-party claims and assertion of intellectual property rights against third-parties. You will have functional responsibilities for: preparing, filing, prosecution, maintenance, and protection of patents; maintaining and tracking regulatory exclusivities for each product (and pruning the IP portfolio as appropriate); performing Freedom to Operate analysis; handling trademark prosecution counseling and enforcement; overseeing IP litigation; providing support for R&D-related agreements, business development (M&A and licensing/development transactions), and other complicated contractual transactions. You will work with external counsel in performing these functions. You will collaborate with the discovery and development functions such as chemistry, CMC, and other teams at Tango. This role offers a broad range of responsibilities and significant growth opportunities in an exciting and growing company. 

Your Role:

  • You will create and execute global IP strategies for all of Tango’s current and future pipeline products
  • Provide IP counseling to in-house clients within discovery and development functions such as chemistry, CMC, and other functional areas through all phases of drug research, development, and commercialization
  • Identify patentable inventions and advise business partners on proper documentation of all inventions to support patentability
  • Prepare patent applications (with the assistance of outside counsel) with a primary focus on composition of matter for synthetic lethal therapeutics and precision medicine synthetic therapeutics
  • Maintain prosecution docket of all U.S. and foreign patent applications, including post-grant practices as they may arise with prosecution
  • Implement trade secret best practices in order to protect technology not subject to patent protection
  • Provide IP counseling to support product lifecycle planning and develop strategies for enhancing exclusivity
  • Support intellectual property-related transactional and litigation work
  • Additional duties and responsibilities as required


What You Bring:

  • Minimum of a bachelor’s degree in chemistry or related field and a JD required
  • A master’s degree or Ph.D. in chemistry or related field is strongly preferred
  • Patent Attorney admitted to practice before US Patent and Trademark Office with at least 6 years' experience that includes working in both a law firm and small molecule pharma/biotechnology company
  • Experience developing global IP strategy required, with the objective of supporting the development of a comprehensive commercial strategy to protect product exclusivity rights
  • Must have direct experience drafting and prosecuting patent applications and conducting or directing Freedom to Operate analyses
  • Ability to counsel in-house clients on complex IP issues and potential implications to current or future business strategies within the field of synthetic lethal therapeutics and precision medicine synthetic therapeutics required
  • Experience with post-grant proceedings (IPRs, reexaminations, and oppositions) preferred
  • Experience with ex-US (including Europe and Japan) patent filing and prosecution preferred
  • Experience with trademark and trade secret protections preferred
  • Licensing and technology transactional experience (including with co-development, co-commercialization, and/or distribution agreements) preferred
  • Previous involvement with due diligence in connection with licensing, collaboration, development, and M&A transactions preferred
  • Ability to work independently and within a team environment
  • Demonstrated ability to respond quickly and flexibly in a fast-paced and rapidly changing environment
  • Developed sense of judgment, risk management skills, and ability to balance legal matters involving multiple stakeholders and various priorities; ability to balance regulatory obligations and reputational risks in an objective, practical way
  • Ability to concisely, succinctly, and clearly communicate complex IP concepts and strategy to stakeholders with limited exposure to IP concepts

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