ShapeTX® is pioneering the field of programmable RNA medicines to repair the genetic causes of diseases. By merging innovations in AI and RNA technology to generate and analyze hundreds of billions of therapeutic possibilities, ShapeTX is developing breakthroughs in RNA editing, next-generation AAVs, and disruptive gene therapy manufacturing. The ShapeTX platform enables pharma innovators to design treatments across a wide range of diseases, including rare genetic disorders as well as debilitating conditions, such as Alzheimer’s, Parkinson’s, and many more. You can find us at shapetx.com and on LinkedIn and Twitter.

At ShapeTX, we are a dynamic team of professionals who are dedicated and passionate about making cures a reality. Through diversity of thought, scientific knowledge, professional rigor and focus we are merging cutting-edge science with extensive drug development expertise to unlock cures to many debilitating diseases.

Shape Therapeutics is headquartered in Seattle, Washington with a satellite site in Boston, Massachusetts.


ShapeTX is looking for a highly motivated, collaborative, and detail-oriented individual to join the growing Operations team as a Laboratory Operations Site Lead. In this role, the successful candidate will be responsible for the oversight of laboratory management including equipment, facilities, shipping and receiving, and day-to-day operations. The ideal candidate must consistently manage multiple efforts while collaborating with revolving stake holders. This role will have the opportunity to immediately impact and foster growth of both laboratory and companywide operations within a fast paced and dynamic science-driven environment.

Roles and Responsibilities:

  • Manage site by ensuring that the office and laboratory runs smoothly on a daily basis and support all general site functions as needed.
  • Develop, maintain and optimize processes within the site to increase efficiency and effectiveness.
  • Establish and implement lab management procedures; create and manage associated documentation.
  • Ensure compliance with applicable facility standards, through site inspections and facilitation of regular internal meetings.
  • Collaborate regularly with scientists to address any workflow bottlenecks, inefficiencies, opportunities for process improvements, and logistical or administrative issues in the lab.
  • Anticipate, troubleshoot, and resolve operational problems, and address occasional lab emergencies.
  • Manage lab safety and regulatory compliance, including tracking of biologics, chemical and hazardous materials, and employing PPE policies and lab safety rules.
  • Oversee Environmental Health & Safety committee and training program.
  • Coordinate ordering, delivery, installation, cleaning, and maintenance of lab equipment.
  • Manage all shipping and receiving, ensuring shipping compliance and safety.
  • Handle vendor management and coordination, including, but not limited to lab coats, bottled gases, dry ice.
  • Oversee waste management programs, including biological and chemical waste streams.
  • Coordinate annual lab permits and license renewals.
  • Oversee site and lab equipment security monitoring systems
  • Oversee and manage lab and office inventories, cleanliness, and general maintenance.
  • Coordinate lab and office space planning, including move-in/move-out efforts for tenants and sub-tenants.

Preferred Qualifications:

  • Bachelor’s degree in scientific discipline with 5 or more years of relevant experience in a biotech/pharmaceutical lab environment or laboratory operations role.
  • Ability to work both independently and collaboratively in a team-science environment.
  • Ability to think outside the box and tackle challenges with a problem-solving, can-do attitude.
  • Exceptional organizational skills, attention to detail and ability to maintain a high standard of confidentiality.
  • Strong follow-up and time management skills with ability to effectively multi-task and a willingness to perform a wide range of tasks.

Skills and Experience:

  • Experience in a laboratory setting and understanding of lab staff needs.
  • Experience with a wide array of equipment such as pipettes, cold storage equipment, molecular biology equipment, and cell culture equipment.
  • Experience with tissue culture and aseptic techniques for cellular and molecular biology
  • Subject matter expertise regarding laboratory safety.
  • Ability to manage equipment inventory and maintenance.
  • Excellent interpersonal skills and ability to be calm and collected in a dynamic environment, and at times, with demanding situations.
  • Effective and proactive communication and ability to collaborate with a wide array of personalities and work styles, and across functional areas.
  • Great attention to detail, including a proven ability to manage multiple, competing priorities simultaneously, as well as the ability to think strategically and execute methodically.
  • Ability to independently manage workflow to see projects through from start to completion.
  • High level of initiative, good judgement, and the ability to work with little supervision.
  • Self-motivated and resourceful.
  • Ability to quickly pivot between tasks and prioritize simultaneous tasks in a fast-paced environment.
  • Strong written and oral communication skills.
  • Stellar work ethic and passion for research.
  • Some weekend work may be required.
  • Ability to lift 50 pounds.

We aspire to Shape Life! not only through our science, but also through our commitment to foster an inclusive environment that supports diverse perspectives and experiences.

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