We’re seeking a Protein Structure Prediction/Optimization Scientist to join us in our mission to improve human health and quality of life through the development, distribution, and application of advanced computational methods!
As a member of our Prime (Protein Structure Prediction) team, you’ll play a key role in the improvement of our structure prediction and homology modeling capabilities. By advancing our methodology and immediately applying it to both our and our customers’ drug-discovery platforms, you’ll help tackle diseases that have been recalcitrant to structure-based drug design in the past. Schrödinger’s recent acquisition of XTAL BioStructures puts us in a unique position to advance the state of the art in protein structure prediction and refinement with experimental validation and support.
A computational chemist who brings experience building homology models of or predicting conformational changes in proteins
A tinkerer who loves taking apart technology to understand how it works, and putting it back together so it works better
A methods developer who can take an idea and implement a prototype using modern coding practices
An enthusiastic learner who enjoys picking up new technological and domain skills
What you’ll do:
Identify flaws and limitations in existing homology models and develop strategies for refinement
Collaborate with scientists in other teams, including Machine Learning and Desmond (Molecular Dynamics), to exploit the latest developments and incorporate them into your projects
Work with our drug discovery group to deploy new technologies in active projects and realize real-world impact
What you should have:
PhD in computational chemistry, biochemistry, biophysics, or a related field
Proficiency in building complex workflows with Python
Robust knowledge of modern developer practices (git, test-driven development)
Experience with compiled languages (C, C++, Fortran) is a plus
Experience with pharmaceutically relevant proteins, such as kinases, GPCRs, proteases, transferases, and/or ion channels is a plus
Pay and perks:
Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office every day, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work for the past three years running.
Sound exciting? Apply today and join us!
As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.