We are seeking a Principal Scientist/Senior Principal Scientist, Immunology Drug Discovery to join us in our mission to discover and develop drugs that improve human health through the use of breakthrough computational methods. We need outstanding individuals to join our drug discovery group and contribute to our rapidly expanding portfolio of drug discovery programs and collaborations. 

Our drug discovery and early clinical development team includes a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers as well as a large-scale computer infrastructure to apply our proprietary physics-based drug design and optimization platform. Ten of the programs we’ve worked on have progressed into preclinical development, with four currently in clinical trials and one approved by the FDA.

Who will love this job:

  • A motivated immunologist who understands immune and inflammatory pathways and how their dysregulation can contribute to disease processes allied with a firm grounding in their supporting preclinical models 
  • An enthusiastic drug discoverer to drive the identification of small molecule drug discovery opportunities in the areas of immunology and inflammatory diseases
  • An experienced manager of external studies at CROs (including study design, monitoring study execution, and timely delivery of study results)
  • An excellent team player who has collaboratively advanced drug discovery programs through preclinical development

What you’ll do:

  • Spearhead the identification of appropriate therapeutic targets across the Immune Disease space and direct drug discovery teams to advance novel molecules to clinical entry
  • Provide scientific leadership in the areas of immunology and inflammatory diseases, including identification of therapeutic target opportunities that are a fit for Schrödinger’s proprietary computational platform
  • Lead interactions with CROs and KOLs, and serve as a disease biology expert on cross-functional discovery teams
  • Advance drug discovery research programs from the preclinical to clinical stage
  • Stay informed on trends and emerging developments regarding R&D in immunology and inflammatory diseases  
  • Contribute to writing documents in support of candidate molecules advancing to clinical entry (i.e., IND filing)
  • Interact with clinical colleagues to define and validate translational biomarker approaches

What you should have:

  • A PhD in Immunology or related field
  • At least three years of experience in the pharmaceutical or biotechnology industries
Pay and perks:
Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office every day, a company culture that is relaxed but engaged, and over a month of paid vacation time.  Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work for the past three years running.
 
Sound exciting? Apply today and join us!
 
As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, or sexual orientation. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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