Pliant Therapeutics is a public, clinical stage biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. Founded by Third Rock Ventures with world-renowned academic thought leaders, Pliant is raising the bar to meet the unmet medical needs of physicians, patients and families impacted by fibrotic disease. The Company’s focus is on mechanism-based intervention in the fibrotic process using small molecules.
The Company’s lead product candidate, PLN-74809, is an oral, small molecule selective inhibitor of the αvβ1 and αvβ6 integrins that play a key role in multiple fibrotic pathways. PLN-74809 has received Orphan Drug Designation from the U.S. Food and Drug Administration in both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) and are currently in Phase 2a clinical trials for these indications. The company recently reported positive data from its Phase 2a trial in IPF and is currently ramping up activities in preparation for a late-stage clinical trial at worldwide sites.
Pliant has also developed PLN-1474, a small molecule, selective inhibitor of αvß1 for the treatment of nonalcoholic steatohepatitis, or NASH with liver fibrosis. Pliant is initiating a Phase 1 study for its third clinical program, PLN-101095, a small molecule, dual-selective inhibitor of αvß8 and αvß1 integrins, that is being developed for the treatment of solid tumors. The Company also has discovery and development programs in oncology and muscular dystrophies.
The Company is seeking passionate, creative, and dedicated individuals to join our team and contribute to our mission.
Description
Under supervision from Director, Legal Operations, the successful candidate will be responsible for the development, negotiation, review, and lifecycle management of contracts supporting Pliant’s early research through IND efforts. On an as needed basis, they will also assist administrative efforts to support Pliant’s Clinical Programs.
Responsibilities
- Draft, negotiate and manage a variety of contracts supporting Pliant’s research and development efforts such as Sponsored Research Agreements, Master Services Agreements, Material Transfer Agreements, and other documents related thereto.
- Develop collaborative working relationships with research staff leaders to understand their research efforts and priorities in order to meet corporate goals.
- Manage a high volume of agreements from start to finish to support scientific and operational needs of Pliant.
- Serve as primary point of contact for business stakeholders on contract matters.
- Understanding of finance and procurement processes.
- Ability to improve existing database of contract forms and support Pliant’s CLM system.
- Work closely with the broad Legal Team to promote and advance all Legal processes along with providing training on commercial and legal terms to the Research Teams at Pliant.
- Working knowledge of Good Clinical Practice (GCP), Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP).
Qualifications
To perform this job successfully, an individual must be able to perform each essential duty. The requirements listed below are representative of the knowledge, skill, abilities and prior experience required.
- BS/BA in business or science required with a minimum of 5-7 years’ experience including prior experience negotiating research contracts in a biotech/pharma company or university setting. JD/MBA preferred.
- Extensive experience negotiating with Academic and Non-Profit institutions such as Universities.
- Demonstrable knowledge of current contracting as well as legal and regulatory environment as it relates to the pharmaceutical/biotech industry.
- Knowledge of the drug development process with a passion for drug development in a Biotech setting.
- Strong interpersonal skills to maintain positive working relationship with internal and external stakeholders.
- Detail-oriented mindset with excellent verbal and written communication skills.
- Ability to work independently while managing to multiple priorities.
- Some knowledge of Data Privacy Regulations/Laws (e.g., GDPR, HIPAA & PIPEDA).
Pliant requires all new hires to be fully vaccinated prior to the first date of employment (subject to any legally required exemptions).
The annual base salary for this role is $150,000 - $165,000. Individual pay may vary based on additional factors, including, and without limitation job-related skills, experience, work location and relevant education or training. Pliant’s compensation package also includes benefits, equity, and annual target bonus for fulltime positions.
To understand how Pliant complies with and manages your personal information with respect to the California Consumer Privacy Act, please visit https://pliantrx.com/ccpa-applicant-and-staff-privacy-notice/.
