Personalis, Inc. is a leader in advanced cancer genomics for enabling the next generation of precision cancer therapies and diagnostics. The Personalis NeXT Platform® is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers and clinicians with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. In population sequencing, Personalis operates one of the largest sequencing operations globally and is currently the sole sequencing provider to Veterans Affairs' Million Veteran Program. To enable cancer and population sequencing, Personalis' Clinical Laboratory was built with a focus on clinical accuracy, quality, big data, scale and efficiency. The laboratory is GxP-aligned as well as Clinical Laboratory Improvement Amendments of 1988-certified and College of American Pathologists-accredited.
As Senior Manager, Technical Operations you will manage a growing team of engineers and scientists to enable efficient and scalable lab processes, execute product and process improvements, validation, and implementation, and provide lab operation support. The ideal candidate is a detail-oriented, dynamic team player with hands-on experience in implementing and troubleshooting both manual and automated Next Generation Sequencing assays and workflows.
Partner with cross-functional teams such as Product Development, Lab, Tech Transfer, LIMS, Supply Chain, Data Analytics, Quality, and Regulatory, to ensure sustainability and scalability of lab operational processes to meet applicable requirements (CLIA/CAP/GCLP/FDA)
Lead or participate in lab operations troubleshooting effort and support non-conformance investigations and corrective action implementations
Support drafting of documentation for process validation, operating procedures, and batch worksheets
Participate in planning and executing development and validation studies to drive operation efficiencies, process improvements, and COGS reduction
Contribute to the Technical Operations team strategic plan to meet growing business needs and evolving regulatory requirements
Establish and track relevant key performance indicators and metrics to drive accountability and manage individual and team performance
Mentor and provide technical guidance to engineers and scientists within the Tech Ops team
Education & Experience:
A BS in Biology, Chemistry, Molecular Biology or related field, an advanced degree strongly preferred
Minimum 5 years of people management experience having hired, trained, and led high performing teams in a fast-paced and dynamic environment
Relevant experience in a CAP/CLIA Laboratory strongly preferred
Practical knowledge of Next Generation Sequencing technologies and sample preparation workflows, experience in automation a plus
Excellent verbal and written communication skills and willingness to collaborate cross-functionally
Strong project management, planning, problem-solving, and organizational skills
Experience in experimental design, implementation, troubleshooting, and data analysis
Proven ability to think innovatively toward solving problems effectively and efficiently
Analytical, detail-oriented, organized, takes initiative, and self-motivated
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package.