Personalis is a rapidly growing cancer genomics company transforming the development of next-generation therapies by providing more comprehensive molecular data about each patient’s cancer and immune response. Our ImmunoID NeXT Platform® is enabling the development of next generation immuno-oncology therapeutics and diagnostics.


The Manager, Business Systems is a critical position for Personalis to ensure the Company can efficiently and accurately record business and financial transactions, management is able to receive timely and useful information about the business and ensure that proper system controls are in place. The Manager, Business Systems will also serve in a strategic role as a dedicated in-house expert regarding the implementation and use of the financial systems including but not limited to QAD ERP, Adaptive Planning, PayChex/ADP, and iPurchase.

Utilize your strong IT skills and broad familiarity of supporting finance organizations to enhance productivity, support the implementation of system controls, and work with other cross-functional team members to all company systems are well integrated.  The role is based in Menlo Park.


  • Improve and maintain financial IT systems for the finance organization, including setting up desired reports and data collections, as required.
  • Interact with all departments including operations, quality, production, purchasing, inventory management, sales, marketing, and finance to assess business processes. 
  • Translate business requirements across the organization into actionable requirements to enhance the use of existing systems and tools, or formulate plans for implementing additional tools.
  • Understand the changes within the business environment, such as new product introductions, changes in accounting standards, and internal process changes to formulate strategies and plans for enhancing internal customer support.
  • Design, develop, and implement tools in order to integrate operational and engineering systems with QAD and other financial systems.  Focus on technical aspects of interfaces and middleware, and engage external service providers when appropriate.
  • Analyze business processes to identify potential enhancements where tools can be used to increase efficiency.
  • Assist with the implementation of internal controls for IT systems.  Manage system and user security, add users, change access, etc. Ensure that proper segregation of duties exist for system access, functions assigned to users, and also, help ensure that SAS 70 reports include appropriate information for compliance.
  • Oversees support of IT compliance requirements related to FDA, SOX, and Security as it pertains to QAD.
  • Support documentation and maintenance of IT policies and procedures related to business applications with strong focus on compliance and security.
  • Train and educate users across the organization on the system capabilities and help ensure that users can be productive.
  • Other projects, and tasks as the Company grows and evolves over time.


  • Bachelor’s degree in Computer Science, or equivalent.
  • Minimum of 10+ years of industry experience in business analyst roles. Strong project management skills helpful.
  • Experience within a manufacturing environment.
  • Prior experience with QAD ERP.
  • Excellent interpersonal skills and communication skills with the ability to present thoughts and information to senior management

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities.  Personalis offers a competitive compensation package. 



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