Personalis is a rapidly growing cancer genomics company transforming the development of next-generation therapies by providing more comprehensive molecular data about each patient’s cancer and immune response. Our ImmunoID NeXT Platform® is enabling the development of next generation immuno-oncology therapeutics and diagnostics.

Summary:

You will join a team of bioinformaticians and software engineers whose mission is to develop robust, high-performance pipelines that can accurately and reliably analyze large volumes of next-generation sequencing (NGS) data. Our pipelines provide the foundation for a wide range of cutting-edge applications in the immune-oncology space, including analysis of diagnostic and emerging biomarkers that enable precision treatment for cancer patients.

We seek a highly skilled leader to build a team to focus on pipeline test infrastructure, and verification and validation analyses. The ideal candidate will bring deep technical leadership with V&V activities centered on bioinformatics pipelines. An essential function of this group will be to develop automated test infrastructure, focused on the robustness and scientific correctness of our pipelines. Experience managing a small team in regulated IVD environments is a major plus.

Responsibilities:

  • Build out a Bioinformatics V&V/Test team within the Bioinformatics Engineering group.
  • Direct the development and execution of our bioinformatics pipeline verification and validation processes.
  • Develop automated testing frameworks for existing and future bioinformatics pipelines.
  • Define requirements for unit and functional tests to be written by development engineers.
  • Coordinate testing of infrastructure changes with Information Technology team.
  • Coordinate coverage of feature and product level testing with the Software QA team.
  • Coordinate with the regulatory and clinical teams on regulatory approvals and clinical validations.
  • Involvement in release planning, writing documentation, and ensuring regulatory compliance.

Requirements:

  • At least 5 years’ industry experience working on pipeline test and verification.
  • Understanding of statistical metrics of accuracy performance, and experience developing and executing test plans to measure them.
  • Experience working in regulated environments such as HIPAA, CAP, FDA.
  • Experience managing a team
  • Fluency in a programming/scripting language such as Python, Bash, R.
  • Extensive background in molecular biology and genomics.
  • Familiarity with standard NGS tools such as BWA and GATK

Education:

  • MS or PhD in a STEM field, or equivalent professional experience.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities.  Personalis offers a competitive compensation package. 

 

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