Principal Scientist II - Downstream Processing

Reports to: Scientific Manager/Associate Director

Location: Bangalore

About the Department 

nth Bio, our enterprise biology platform, is the first of its kind to help partners of all sizes join us in creating a kinder, greener future through precision fermentation. nth Bio is focused on piloting and scaling our technology to partners across industries, including food, agriculture, pharmaceutical, biologics, textile, and personal care to create products in a new, sustainable way. 

Position Summary 

The position is responsible for planning and execution of downstream Process development, Scale-up, Technology Transfer, and Lab management.

What You Will Do

• Principal Scientist person will be responsible for planning, execution trouble shooting of Downstream Process execution/deliverables for microbial products.
• Accountable for data capturing, compilation, interpretation in coordination with manager and presentation preparation
• Preparation and/or review of development reports, TTD, BPR, SOP, EOP, IOP and technical presentations.
• Responsible for scale-up and technology transfer related activities.
• Team management of (2-3 No team) and mentoring the interns / team members
• Lab Management: Maintaining the downstream equipment's qualification and training to subordinates.
• Responsible for activities related to departmental audits, responding audit observations in coordination with manager.
• Cross-functional communication with internal and external customers (vendors/clients) for technical queries
• Maintain environment, health, and safety (EHS) requirements always in the workplace ensuring individual and lab/plant safety.
• Troubleshooting of technical problems
• Work experience in downstream processing in a biotechnology company or CMO is an advantage.

What You Bring     

We have an opportunity to collaborate to use our unique contributions to create a kinder, greener tomorrow. The dynamic employee we seek is a (Principal Scientist II) with these qualifications.

Education, Experience & Other Requirements

To be successful in this position, we expect candidates to have the following technical qualifications:

• Ph.D.: 0-2 years relevant experience
• M Tech/ M Sc/B. Tech with 8-10 years of Experience (Life science, Biotechnology)

Knowledge, Skills & Abilities: 

• Small Molecule (Antibiotics, peptides) purification expertise, preferably in microbial hosts
• Proficient in downstream process scale-up, technology transfer, process troubleshooting.
• Use Design of Experiment (DoE) to screen purification conditions and optimize the process.
• In-depth knowledge of downstream processing techniques like Membrane filtration (TFF), Precipitation, Solvent extraction, crystallization and Spray drying.
• Excellent team player and multitasking
• Strong commitment and dedication towards work, enthusiasm, motivation, and persuasive ability in a team.
• Conduct technical investigations and risk assessments related with processes and provide process expertise in the resolution of complex technical or operational problems.
• Perform independent data recording, analysis and troubleshooting and support generation of SOPs, raw material specifications, batch records, and reports.
• Ability to independently make decisions based on data, scientific knowledge, and sound judgement.
• Good speaking-listening-writing skills, attention to detail, proactive and self-starter.
• Work in a Dynamic, ambiguous environment with a timeline.

Language Skills

Skills that enable a person to communicate orally or in writing in English. These include reading, writing, listening, and speaking.

• Active Listening
• Speaking Impactfully
• Proficient Writing
• Attention to Detail