Position Overview

As a member of the Platform team, the Analytical Chemist is responsible for performing laboratory work in support of analytical testing of pharmaceutical projects. Responsibilities may include running analytical methods, performing stability and release testing, testing to support pharmaceutical development efforts, and documentation of experimental results. The ideal candidate will have impeccable attention to detail, be a strong written and verbal communicator, and be able to thrive in a fast-paced environment.

Essential Functions

  • Execute, improve and develop analytical methods to support upstream and downstream process development
  • Independently analyze and provide conclusions regarding experimental data generated
  • Present problems and propose solutions in discussions with group members
  • Perform timely notebook entries and review for completed experiments
  • Satisfactorily complete all GLP and safety training in compliance with departmental requirements and follow appropriate safety practices in the workplace
  • Perform all compound management workflows and tasks including manual transfer and weighing of compounds in powder format, compound dissolution, and preparation of compound solutions in plated formats using both manual and automated systems
  • Provide support for HTS screening and hit-to-lead efforts using automation, liquid handling, inventory management tools
  • Generate compound plates on set schedule for weekly profiling assays
  • Run analytical HPLC/LCMS methods for QC and assays to characterize compounds and develop new methods as needed
  • Prepare shipping manifests and documentation for domestic and international shipment
  • Maintain electronic lab notebooks for documentation
  • Develop methods for liquid handlers, tube sorters, barcode readers and other automation
  • Work closely with Research Informatics to identify and implement process changes to streamline throughput, including the introduction of process automation
  • Collaborate with scientists from multiple disciplines, internal and external, to design and implement workflows when needed
  • Maintain laboratory instruments in good operating condition and perform basic troubleshooting
  • Work Safety – Ensure that all tasks and functions of position are always performed in a safe manner and that all procedures and requirements are properly followed to accomplish assigned tasks
  • Other duties as assigned

Required Qualifications and Skills

  • BS/MS in Chemistry, Biochemistry or related discipline
  • At least five years hands-on experience in compound management and an excellent understanding of underlying processes
  • Proven capabilities to think critically and creatively and to work independently
  • Expertise operating, programming, and troubleshooting various instrumentation such as weigh stations, automated compound stores, HPLC/LCMS, liquid handlers, acoustic dispensers, plate handlers, and tube sorters
  • Proven analytical abilities with high attention-to-detail and strong record-keeping as demonstrated through past experience
  • Previous experience with SEC/GPC or another polymer characterization a plus
  • Familiarity with data acquisition software such as ChemStation, Masshunter
  • Familiarity with Titration KF, spectroscopy, IR, UV-Vis, colorimeter preferred
  • Experience with analytical method transfers to external organizations preferred
  • Strong communication and organizational skills
  • Strong team orientation; highly collaborative and flexible
  • Ability and desire to work in a fast-paced environment
  • Live near or willingness to travel to Pittsburgh, PA

Diversity & Inclusion: Our Foundation for Innovation

At Peptilogics, diversity, inclusion and equality are embedded in our DNA. Together, regardless of gender, race, ethnicity, national origin, age, sexual orientation or identity, education or disability, the Peptilogics team envisions a workplace where all employees feel valued and respected. We provide equal employment opportunities to all employees and applicants as we continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our team members. 

Peptilogics is committed to serving as a model of diversity and inclusion for the entire biotech and biopharmaceutical industry and to maintaining an inclusive environment with equitable treatment for all. It fuels our innovation, reinforces our vision, and more closely connects us to the communities we serve.

Peptilogics complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Peptilogics is an E-Verify employer.

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