The brief: Transform measurement in medicine. PatientsLikeMe is a patient network that improves lives and a real-time research platform that advances medicine. Through the network, patients connect with others who have the same disease or condition, and track and share their own experiences. In the process, they generate data about the real-world nature of disease that help researchers, pharmaceutical companies, regulators, providers, and non-profits develop more effective products, services and care. With more than 550,000 members, PatientsLikeMe is a trusted source for real-world disease information and a clinically robust resource that has published more than 100 peer-reviewed research studies.

Our R&D team is embarking on new avenues of research combining the patient-reported experience of disease with biological data, objective sensors, and machine learning. As a Director of Outcomes Science focused on patient-reported outcomes you will use your scientific leadership, analytic skills, and experience to conceive, design, and execute high-quality health outcomes research projects in collaboration with our business, consumer-centered design, and computational biology teams. In addition to being an expert researcher, you will succinctly communicate the key findings to diverse audiences including scientists and senior business executives. As a leader in the organization, you will build a team and a strategy to help transform measurement in medicine. As a member of the PatientsLikeMe team, you will share lessons learned from each project to help us improve our platform, enhancing the patient’s ability to find other patients who can inform, support, and educate each other.


  • Put patients first in everything that you do
  • Take responsibility for the continued development and validation of our “Thrive” measurement system, which aims to generate dynamic PRO-like scores for symptom burden, disease impact, and self-perception which allow individuals to better manage their disease and for researchers to make novel biological discoveries
  • Manage a portfolio of work in psychometric and clinical validation across multiple conditions including internal work upgrading our patient platform and external collaborators
  • Translate requirements from customers (external and internal) and develop and execute methodologically rigorous research designs to answer their questions and solve patients’ problems using the data gathered in our longitudinal registry
  • Lead meetings with prospective collaborators, explaining our capabilities and methods as well as developing study goals/requirements and turning these into robust proposals
  • Supervise and oversee concept elicitation, qualitative, and quantitative analyses in the context of the existing scientific literature and design studies that clearly answer research objectives
  • Work on cross-functional teams (health data integrity, clinical research, consumer-centered design, business) to produce research insights and effectively communicate with the client/stakeholder throughout the research process
  • Participate in preparing and delivering client presentations
  • Supervise research scientists, research assistants, and consultants working on projects
  • Develop a publication strategy including conference presentations, posters, and peer-reviewed journal articles
  • Participate in the scientific literature as a peer reviewer and thought leader


  • Master's, PhD, or MD-level education in the field of psychology, epidemiology, psychometrics, statistics, clinical research, public health, or related field
  • Expertise in multiple academic and/or commercial patient-reported outcomes development projects as lead decision-maker. International reputation a plus
  • 7+ years of post-training experience in human clinical research; demonstrated experience in research design, data collection, managing data sets, qualitative data analysis, and psychometrics.
  • Preferred – Experience combining patient outcome data with biological data (e.g. genetics, proteomics, immunology, objective sensors, medical devices, metabolomics, lab values)
  • A record of peer-reviewed publications related to patient-reported outcomes measures as first or senior author.
  • Editorial board experience a plus Commitment to excellence in managing teams and continuing personal development
  • Experience working directly with commercial and/or academic sponsors in identifying and conceptualizing patient reported outcome projects
  • Proficiency with statistical software programs such as SAS, R, Stata, or SPSS Industry experience in pharmaceutical outcomes research, epidemiology, HEOR, or data informatics
  • Local to the Boston/Cambridge area and able to be onsite daily, up to 10% travel
  • You should become very familiar with our vision, our website, and our research before applying; check out our publications, YouTube presentations, and our blog. Learn more about life at PatientsLikeMe here.  
  • In your cover letter, please highlight your best work, what you can bring to the team, and why you are interested in PatientsLikeMe. 


Apply for this Job
* Required
Almost there! Review your information then click 'Submit Application' to apply.

File   X
File   X

U.S. Equal Opportunity Employment Information (Completion is voluntary)

Individuals seeking employment at PatientsLikeMe are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. You are being given the opportunity to provide the following information in order to help us comply with federal and state Equal Employment Opportunity/Affirmative Action record keeping, reporting, and other legal requirements.

Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Form CC-305

OMB Control Number 1250-0005

Expires 1/31/2020

Voluntary Self-Identification of Disability

Why are you being asked to complete this form?

Because we do business with the government, we must reach out to, hire, and provide equal opportunity to qualified people with disabilities1. To help us measure how well we are doing, we are asking you to tell us if you have a disability or if you ever had a disability. Completing this form is voluntary, but we hope that you will choose to fill it out. If you are applying for a job, any answer you give will be kept private and will not be used against you in any way.

If you already work for us, your answer will not be used against you in any way. Because a person may become disabled at any time, we are required to ask all of our employees to update their information every five years. You may voluntarily self-identify as having a disability on this form without fear of any punishment because you did not identify as having a disability earlier.

How do I know if I have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:

  • Blindness
  • Deafness
  • Cancer
  • Diabetes
  • Epilepsy
  • Autism
  • Cerebral palsy
  • Schizophrenia
  • Muscular dystrophy
  • Bipolar disorder
  • Major depression
  • Multiple sclerosis (MS)
  • Missing limbs or partially missing limbs
  • Post-traumatic stress disorder (PTSD)
  • Obsessive compulsive disorder
  • Impairments requiring the use of a wheelchair
  • Intellectual disability (previously called mental retardation)
Reasonable Accommodation Notice

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

1Section 503 of the Rehabilitation Act of 1973, as amended. For more information about this form or the equal employment obligations of Federal contractors, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Share this job: