About Omega Therapeutics:

Omega Therapeutics is a Clinical-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as a new class of programmable epigenetic medicines by leveraging its OMEGA Epigenomic Programming™ platform. The OMEGA™ platform harnesses the power of epigenetics, the mechanism that controls gene expression and every aspect of an organism's life from cell genesis, growth and differentiation to cell death. Using a suite of technologies, paired with Omega’s process of systemic, rational and integrative drug design, the OMEGA platform enables control of fundamental epigenetic processes to correct the root cause of disease by returning aberrant gene expression to a normal range without altering native nucleic acid sequences. Omega’s engineered, modular, and programmable mRNA-encoded epigenetic medicines, Omega Epigenomic Controllers™, target specific intervention points amongst the thousands of mapped and validated proprietary and novel DNA-sequence-based epigenomic loci, EpiZips™ to durably tune single or multiple genes to treat and cure disease through Precision Genomic Control™. Omega is currently advancing a broad pipeline of development candidates spanning a range of disease areas, including oncology, regenerative medicine, multigenic diseases including immunology, and select monogenic diseases.

About the Role:

Omega Therapeutics is seeking an experienced, versatile, and hands-on R&D Program Manager to provide strong leadership, strategic direction and program management to program teams. The role is highly cross-functional with key interactions with research, preclinical, CMC, clinical, regulatory, and finance.

The Program Manager, in partnership with the Program Leads, will develop the integrated development plan; will have a firm understanding of the program strategy, critical path activities, risks and mitigation plans; and lead the long-range planning.

The successful candidate will be curious, highly organized, detail oriented, possess a firm understanding of the drug development process, be comfortable with ambiguity, and have a proven track record managing and driving program teams. Furthermore, the successful candidate will have strong communication skills, enabling effective communication within program teams and throughout the organization.

This is an exciting and visible role for a highly qualified and motivated individual. The role will be reporting to the Executive Director of Program and Alliance Management.

Key Responsibilities:

  • Partner closely with Program Leaders to drive the development and execution of strategic, integrated development plans
  • Effectively communicate with cross-functional team members, senior leaders, and key stakeholders on the status, objectives, risks, and mitigation plans associated with projects
  • Build and maintain detailed integrated program timelines
  • Lead scenario planning and analysis
  • Identify bottlenecks and issues and proactively drive for their resolution
  • Track and monitor key milestones and decision points to drive delivery of program objectives
  • Facilitate team meetings using project management best practices/tools to drive cross-functional communication, timely and effective decision making, and successful execution of project objectives
  • Develop and maintain risk registry along with team communications including action item and decision logs, meeting agendas, and minutes
  • Develop project management tools/templates to facilitate timely communication and execution of projects
  • Lead budgeting/forecasting/long-range planning activities for assigned projects

 Required Skills:

  •  Strong leadership skills, including demonstrated ability to lead a cross-functional team, and to influence at all levels of an organization
  • Strong analytical, problem solving and critical thinking skills, including an ability to combine attention to detail with a big picture perspective
  • Excellent oral and written communication skills, including presentation and facilitation skills, to effectively inform key updates and issues across all levels of the organization
  • Ability to work independently and successfully in a fast-paced, results-driven, highly accountable environment with large potential impact; ability to prioritize and manage multiple tasks simultaneously, integrate cross-functional issues, and balance competing priorities effectively
  • Expertise in Microsoft suite (e.g. Project, PowerPoint, SharePoint, Word, Excel, Visio, Outlook etc.) and PM tools (e.g. Office Timeline Pro, OnePager etc.)

Required Qualifications:

  • Bachelor’s degree in life sciences or related field, advanced degree (MS, PhD or MBA) and/or PMP Certification preferred
  • A minimum of 10+ years of experience with a minimum of 8+ years of program management in the biotech/pharmaceutical industry
  • Strong understanding of drug development, including Regulatory Filings. Pre-IND experience (including IND filing) is required
  • Alliance management experience preferred
  • Previous experience in gene editing, gene therapy or cell therapy preferred

Apply for this Job

* Required
resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Omega Therapeutics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Form CC-305

OMB Control Number 1250-0005

Expires 05/31/2023

Voluntary Self-Identification of Disability

Why are you being asked to complete this form?

We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years.

Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:

  • Autism
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
  • Blind or low vision
  • Cancer
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or hard of hearing
  • Depression or anxiety
  • Diabetes
  • Epilepsy
  • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
  • Intellectual disability
  • Missing limbs or partially missing limbs
  • Nervous system condition for example, migraine headaches, Parkinson’s disease, or Multiple sclerosis (MS)
  • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.