We seek a Pharmacometrician for exciting opportunities within our growing firm to work with industry-leading consultants in modeling and simulation. The successful candidate will possess an understanding of pharmacometrics, pharmacokinetics, PK/PD, and modeling concepts and applications. Excellent writing, communication, and mathematical skills are requisite to success in this position.
Contribute to or conduct population PK and PK/PD modeling and simulation projects using industry standard software tools, including model development, validation, and refinement
Work with other scientists to prepare and review population PK reports and other clinical pharmacology documents.
Assist with development and validation of programming code in relevant software for PK, PK/PD, and population PK analyses
Contribute to or conduct non-compartmental and compartmental pharmacokinetic analysis using rich sampling data as needed
Assist with providing strategic advice to clients and developing clinical pharmacology strategic plans and clinical protocol development
Author clinical protocols and clinical pharmacology and pharmacokinetic sections of regulatory documents, including INDs, NDAs, briefing packets, Investigator Brochures, etc.
Assist with the design, analysis, and interpretation of studies involving sparse sampling and provide guidance to optimize PK sampling and dosing strategies
Support client’s nonclinical efforts to ensure that sufficient preclinical PK data exists to design and support clinical studies and model development
Maintain current knowledge of advancements in modeling, simulation, PK, and PK/PD science, regulatory guidance documents, FDA rulings, and internal SOPs to be able to contribute ideas to improve technologies and procedures for PK practices
M.S. or Ph.D. in pharmacometrics, pharmacokinetics, pharmaceutical sciences, pharmacology, biostatistics, or similar disciplines where modeling and simulation is emphasized
3+ years of industry experience in practical applications of modeling and simulation required
Proficiency in NONMEM, R, and Phoenix (WinNonlin® and NLME®) preferred
Benefits and Perks:
Great Medical, Dental, and Vision plans (Vision is covered 100% for all employees and their families)
401(k) and student loan matching
Flexible work environment including weekly remote work options
Paid childbirth and childcare leave
Paid 5 week sabbatical after 5 years of employment
Stocked kitchen with drinks, goodies, and snacks
Frequent company and team-building events
Monthly gym reimbursement
8 hours of paid volunteer time-off
Diversity is a key to success. We are an equal opportunity employer and welcome applicants of all backgrounds, experiences, and perspectives.