We are seeking a motivated and passionate Scientist to elucidate the cell biology of novel gene editing tools as a member of the Mammalian Cell Translation team. This position will play a pivotal role in understanding the cell biology of our novel tools to optimize their function, including designing, optimizing, and implementing high-throughput pooled screens.

You will have the opportunity to make a lasting impact as you partner with in silico biologists, protein engineering, automation, and pre-clinical teams in order to bring the next generation of gene editing therapies to patients. This role will be based in Emeryville, California

About the Role

  • Design, optimize, and execute high-throughput pooled screens to determine strategies to improve the performance of editing systems
  • Establish custom assays to deeply characterize the impact of novel gene editing tools on cell biology
  • Work cross-functionally across Metagenomi to move findings forward
  • Prepare accurate and timely data summaries and contribute to the writing of reports, papers, and patents
  • Manage one or more direct reports

Desired Qualifications 

  • PhD degree in Molecular, Cell Biology or a related discipline
  • Hands-on biotech industry experience with:
    • mammalian cell culture, gene editing technologies, pooled and/or arrayed cell-based screening
    • lentiviral workflows
    • flow cytometry and/or NGS analysis
  • Strong oral and written communication, prioritization and organizational skills
  • Able to quickly learn and adapt to new software tools (Google Suite, Slack)
  • Highly collaborative, solutions oriented, and thrives in a fast-moving startup environment

The anticipated base salary range for this position will be $115,000 - $130,000 depending on the exact level of the role. As this role is open to candidates with a wide range of skills and experience, the exact salary will be dependent on the specific level of the position. We value transparency and will make every effort to provide you with a succinct explanation for how the final salary within this range is determined.


Please note, all candidates must be authorized to work in the United States.


About Metagenomi

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.


What makes Metagenomi a unique place to work?

  • We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
  • We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more! 
  • We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.


At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.


Applicants/Employees have rights under various State and Federal Employment Laws, including

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Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.


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