We are seeking a motivated and detail-oriented Scientist to join our growing Preclinical Team.  In this role, you will contribute to the design, production, and testing of AAV vectors to deliver novel editing tools to cells of interest.  This role will be based in Emeryville, California

About the Role

  • Lead AAV engineering efforts to deliver new genome editing technologies to immortalized and primary mammalian cells
  • Perform in vitro assays to assess viral packaging efficiency
  • Perform cell-based assays to assess cargo delivery and efficacy
  • Analyze complex data sets and recommend next steps
  • Gather and analyze experimental data
  • Present at external scientific meetings
  • Prepare accurate and timely data summaries, contribute to the writing of reports, and present findings to key stakeholders

Desired Qualifications 

  • Ph.D. in biology or a related discipline and 1+ years hands-on industry or academic experience with AAV design, production, and optimization
  • Experience working with immortalized and primary human cells
  • Hands on experience with genome editing technologies in mammalian cells
  • Experience with next generation sequencing technologies and digital droplet PCR (ddPCR)
  • Excellent organizational skills and both oral and written communication skills
  • Thrives in a collaborative and dynamic start-up environment
  • Ability to think strategically, manage time and workflow, and work independently as well as in a results-oriented research team.

The anticipated base salary range for this position will be $115,000 - $130,000 depending on the exact level of the role. As this role is open to candidates with a wide range of skills and experience, the exact salary will be dependent on the specific level of the position. We value transparency and will make every effort to provide you with a succinct explanation for how the final salary within this range is determined.


Please note, all candidates must be authorized to work in the United States.


About Metagenomi

Metagenomi is a gene editing company committed to developing potentially curative therapeutics by leveraging a proprietary toolbox of next-generation gene editing systems to accurately edit DNA where current technologies cannot. Our metagenomics-powered discovery platform and analytical expertise reveal novel cellular machinery sourced from otherwise unknown organisms. We adapt and forge these naturally evolved systems into powerful gene editing systems that are ultra-small, extremely efficient, highly specific and have a decreased risk of immune response. These systems fuel our pipeline of novel medicines and can be leveraged by partners. Our goal is to revolutionize gene editing for the benefit of patients around the world. For more information, please visit https://metagenomi.co/.


What makes Metagenomi a unique place to work?

  • We are passionate about developing technologies derived from microbial-rich ecosystems that have the power to enable therapeutic development and the potential to cure devastating disease.
  • We have cultivated an amazing culture that values teamwork, curiosity, scientific rigor, and fun. We have a strong commitment to work/life balance, host a weekly employee happy hour and events, provide catered lunches and endless snacks, and more! 
  • We offer competitive compensation including a market-benchmarked salary, annual target bonus, equity in an early-stage startup, and a comprehensive benefits plan, including 401(k) matching, a retirement safe harbor plan, and other perks.


At Metagenomi, we know that our people drive our success. We are an equal-opportunity employer and believe in and value diversity and inclusion. Metagenomi provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers. Metagenomi does not discriminate on the basis of race, color, religion, sexual orientation, gender, age, physical or mental disability, or any other status protected under federal, state, or local law. Please note, all candidates must be authorized to work in the United States.


Applicants/Employees have rights under various State and Federal Employment Laws, including

without limitation:







Notice to agencies: Our in-house Talent Acquisition Team manages all employment opportunities at Metagenomi. Agencies and independent recruiters must be approved as a vendor by Metagenomi’s Talent Acquisition team. To protect the interests of all parties, Metagenomi will not accept unsolicited resumes, profiles, or biographies. Any unsolicited resumes sent to Metagenomi will be considered referrals and the property of Metagenomi.


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