Matchpoint is a biotechnology company harnessing the power of covalency to discover precision covalent medicines to transform the treatment of immune diseases and other serious illnesses. The company's proprietary Advanced Covalent Exploration (ACE) platform integrates advanced chemoproteomics, machine learning and covalent chemistry library evolution. Matchpoint has an emerging pipeline of novel covalent medicines initially focused on immunology.

Founded in 2021 by Atlas Venture and Access Biotechnology together with leading scientists from the Dana Farber Cancer Institute and Stanford, we are rapidly growing our team and looking for passionate, driven, and creative thinkers to join us in ushering in a new era of covalent medicines.

Position Summary

Matchpoint Therapeutics is looking for an experienced, collaborative, and driven Controller / Director of Finance to report to the Vice President of Corporate Development and Operations to oversee day to day financial operations and contribute to long range planning.  As the first dedicated finance hire in a fast paced and growing small molecule discovery company, the Director of Finance needs to be a self-starter; maintaining focus on the day to day, while ensuring we lay the groundwork for the next stage of Matchpoint’s growth.

The successful candidate will be comfortable operating in a highly matrixed team environment; partnering with the VP of Corporate Development and Operations to plan for and manage the financial aspects of the business.

Key Responsibilities 

  • Accounting / Budget
    • Lead all aspects of day-to-day accounting, supervising outsourced accounting services as needed such as Accounts Payable and General Ledger Management
    • Responsible for consolidated financial results by overseeing consolidated monthly and quarterly financial close processes
    • Ensure the timely and accurate delivery of financial results to management
    • Oversee management of cash; ensuring appropriate distribution of funds across Matchpoint’s operating and MSC accounts on an ongoing basis
    • Conduct financial modelling and other similar ad hoc requests
  • Financial processes
    • Responsible for overseeing and evolving our financial internal controls and governance policies and processes to support Matchpoint’s current operations and future growth. This includes but is not limited to the oversight / management of general ledger codes, PO processes, expense reporting.
    • Serve as primary point of contact for internal and external parties on finance related topics
    • Responsible for a range of financial projects executed by external firms: including tax filings, audits, technical accounting, and 409a valuations
    • Lead implementation of financial systems, including the conversion from Quickbooks to Net suite
  • Annual / Long Range Planning
    • Partner with the leadership team and manage the budget process in association with other planning activities (goals, hiring, etc)
    • Provide guidance to management on situations that will greatly affect the company's overall financial condition
  • Other business operations
    • Drive onboarding (payroll, benefits) for new employees
    • Work with benefits brokers to setup and maintain health benefits
    • Maintain census and employee records
    • Oversee the 401(k) plan, compliance, and reporting
    • Maintain corporate insurance policies and other business administration responsibilities
    • Maintain a contract log to help understand past, current, and future financial obligations


  • CPA or equivalent work experience
  • 7+ years of experience in a finance role (controller, financial analyst, etc), with at least 4 in the biotech industry
  • Excellent interpersonal skills with a proven record of empowering world class science and energizing teams
  • Proven track record of striving for high level innovation and scientific excellence
  • Flexibility to adapt to rapidly changing priorities and deadlines
  • Ability to work in a team-based environment
  • Excellent oral and written communication skills


We offer a competitive compensation package, including equity-based compensation, annual bonus potential, healthcare benefits, 401(k), parking, and flexible paid time-off. 

Matchpoint is an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, marital or veteran status, disability, or any other legally protected status.

Apply for this Job

* Required
resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Matchpoint Therapeutics ’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Form CC-305

OMB Control Number 1250-0005

Expires 05/31/2023

Voluntary Self-Identification of Disability

Why are you being asked to complete this form?

We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years.

Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at

How do you know if you have a disability?

You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:

  • Autism
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
  • Blind or low vision
  • Cancer
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or hard of hearing
  • Depression or anxiety
  • Diabetes
  • Epilepsy
  • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
  • Intellectual disability
  • Missing limbs or partially missing limbs
  • Nervous system condition for example, migraine headaches, Parkinson’s disease, or Multiple sclerosis (MS)
  • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.