At Lyell, our vision is to develop curative cell-based immunotherapies for solid tumor cancers. We have innovative science originating from our founder’s world class labs and a unique and disruptive approach to research and development. Our company is first and foremost focused on understanding the science. We are a learning organization, dependent on deep collaborative relationships between all of our colleagues, partners and founders. Our culture is based on Respect, Science, Courage and Collaboration and it reflects who we are and the environment we are creating.

POSITION SUMMARY:

The VP of Clinical Development will plan, implement and direct the daily operation of clinical stage drug development projects for the company. Collaboration with key internal and external stakeholders will be key to support company initiatives that improve the quality and content of all clinical programs to achieve our strategic goals.

KEY ROLE AND RESPONSIBILITIES:

  • Establish clinical development plans (clinical strategy) that integrate pre-clinical and early clinical findings while working to ensure cross-functional alignment on an ongoing basis throughout the phases of clinical development
  • Design, prepare, and review study protocols and other required documentation in compliance with GCP and good medical practice.
  • Provide clinical and scientific input during the development, execution and completion of clinical trials. Interpret clinical trial data, prepare clinical study reports, regulatory submission and publications based on the results.
  • Lead development of clinical study documents to be used in regulatory interactions and filings and serve as medical representative with regulatory agencies
  • Evaluate safety, pharmacology, and efficacy data from ongoing and completed studies to inform clinical strategy
  • Manage the safety monitoring of clinical trials and prepare safety reports
  • Present and defend clinical development plans/designs at internal governance forums
  • Prepare and review investigator brochure and annual reports
  • Guide partnered development programs and clinical protocols using Lyell technology
  • Stay abreast with external competitions and treatment landscape
  • Participate in or lead the clinical advisory board meetings to obtain strategic insights for clinical development plan

REQUIRED EDUCATION: 

  • MD with a minimum of 5 years’ experience; Medically licensed, Fellowship and/or Board certification in oncology

PREFERRED EDUCATION:

  • PhD in immunology, oncology or related field strongly recommended

EXPERIENCE:

  • 3+ years as a Medical Director in the biotech or pharmaceutical industry
  • Clinical Oncology experience with a focus on solid tumors
  • Early and late phase clinical trial experience
  • Pre-IND and IND submissions 

KNOWLEDGE, SKILLS AND ABILITIES:

  • Strong team interaction and communication skills
  • Strong leadership presence and the ability to work effectively with other clinical and scientific leaders.
  • A passion for helping patients with cancer and for the science of oncology
  • Collaborative style with internal company leadership, external development partners and investigators/medical professionals
  • Works well in a team environment both as a leader and a key contributor
  • Troubleshoots problems and comes up with solutions or options for discussion

PROBLEM SOLVING:

Troubleshoots and solves complex technical problems within their own projects and within other areas of Research and Development. Identifies issues and communicates them to the group independently. Contributes significantly to functional strategy.

DECISION-MAKING:

Decisions typically impact a function although may have cross-organization influence. Decisions are guided by policies, procedures and function objectives. Makes decisions about the direction of the project, experimental direction, modifications and analysis independently. Can decide to integrate new types of analysis to improve data through collaborations. Decisions can impact analysis and timelines.

At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees.
Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.
 
The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.  This position requires you to work onsite at the Company’s facilities and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law).  Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law.  The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine.  The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.
 
We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply.

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