The Role:

Technology Development at Life Edit Therapeutics discovers and establishes CRISPR genome editing capabilities through protein and RNA engineering and optimization. We also contribute to early therapeutic leads that support internal and external programs for curative gene and cell therapies.  We are looking for an experienced scientist with a strong background in CRISPR engineering and therapeutics to lead our protein engineering projects aiming to deliver effective genome editors for downstream therapeutic programs. This is an exciting opportunity to grow leadership skills, contribute to the making of genetic medicines that impact patients’ lives, and help build a successful therapeutics company from an early stage.

Here’s What You’ll Do:

  • Guide the strategy and direction of engineering CRISPR genome editors for therapeutic targets.
  • Provide expertise in establishing and executing high throughput platforms for protein and/or guide RNA engineering that improve activity and specificity of genome editing both in vitro and in vivo.
  • Work with multidisciplinary teams and program managers to achieve project milestones on time.
  • Mentor junior scientists both in conducting successful engineering projects and in career development.
  • Analyze experimental results and communicate data at internal and external research meetings.
  • Contribute to publications and patent applications.
  • Follow advancements in the field of gene editing and gene therapy published in the literature and presented at conferences.

Requirements:

  • Ph.D. in Biochemistry, Molecular Biology, Cell Biology, or a related field that involves using gene editing systems for therapeutic genome editing.
  • 10+ years post-graduate relevant experience with 4+ years in industry that directly involves engineering and optimizing gene editing systems for therapeutic programs.
  • Experiences in high throughput screening and selection-based directed evolution for protein and guide RNA engineering in bacterial and/or mammalian cells.
  • Experience in early discovery in a CRISPR-based gene and cell therapy company is highly preferred.
  • Demonstrated ability to lead a team and collaborate in a team-oriented environment.
  • Strong oral and written communication skills

We’re committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start.

Health & Wellness

  • Medical, vision, and dental insurance covered at 90%
  • Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
  • Annual fitness reimbursement
  • Employer paid for access to wellness apps and programs like Task Human

Financial

  • Competitive compensation
  • 401(k) retirement plans with a 4% employer match and no vesting period
  • Employer-paid life insurance and short- and long-term disability insurance
  • Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA)
  • Access to a 1-on-1 financial advisor
  • Commuter reimbursement benefit
  • Monthly cell phone stipend

Time Off & Flexibility

  • Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
  • 18 paid company holidays, plus an end-of-year holiday shut down
  • 12 weeks of parental leave
  • Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum

Development Journey

  • Insights Discovery training for every employee to make the most of workplace relationships
  • Ongoing professional development, including manager training
  • Access to LinkedIn Learning, a self-guided online education platform

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics.Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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