Company Information

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.  

Legend Biotech entered into a global collaboration agreement with Janssen Biotech, Inc. to develop, manufacture and commercialize ciltacabtagene autoleucel (cilta-cel). Through our strategic partnership, we look to advance the promise of an immunotherapy in the treatment of multiple myeloma.

About the job

Legend Biotech is seeking an IT SAP S4 Support Specialist as part of the IT team based in Ghent, Belgium.


Role Overview

This individual will be responsible for handling day-to-day IT activities as part of the SAP S4 Global template implementation to support the cGMP Clinical and Commercial Cell Therapy Manufacturing facilities in Ghent, Belgium.

The individual will provide SAP support related activities across different SAP modules, primarily within SAP PP-QM-EWM modules as well as integrations with external MES and eLIMS systems.

Liaise with Legend SAP Development team and 3rd parties on issue resolution as required.



Major Responsibilities

  • Works as the first point of contact with the user community, service delivery of SAP S4 application support, and operations. 1st, 2nd and (potentially) 3rd Level Support.
  • Assesses/analyses S4 issues and determines support/problem resolution where applicable.
  • Monitors and provides follow up instruction on outstanding issues in a timely fashion.
  • Configures (some) application changes within the SAP Implementation Guide (IMG), in alignment with the Global S4 Development team.
  • Tests and analyzes new configuration and validates transfers to production.
  • Ensure major incident communication to management and internal customers.
  • Appropriately escalate issues to S4 Development team (offshore, US based) and/or local management
  • System Monitoring and Improvement (end-user access review procedures, etc)
  • Process Monitoring for IT internal process


  • A minimum of a Bachelor’s Degree in a relevant discipline such as IT or Engineering
  • A minimum of 5 year’s relevant working experience in biotech and/or pharmaceutical industries
  • Experience in supporting SAP solutions used for GMP manufacturing, with focus on PP-QM-EWM modules
  • Knowledge of SAP integration technology (IDoc)
  • Knowledge of Computerized System Validation procedures
  • Knowledge and experience in manufacturing IT system integrations, such as MES with ERP
  • Work in a matrixed team for support execution and delivery
  • Excellent written and verbal communication skills
  • Strong ability to work independently and manage one’s time, be a collaborative team member


Language Requirement

  • Fluent in English 
  • Fluent in Dutch


Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

Legend Biotech maintains a drug-free workplace.

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