The Opportunity

insitro is changing the way that drugs are discovered and developed for patients. We are building a platform that generates novel insights from applying machine learning to a combination of high-quality cellular data generated in-house, and externally sourced human cohort data.

We are looking for a finance leader with a strong financial acumen and demonstrated Anaplan system experience in executing financial budgeting and actuals reporting within the Life Sciences industry. You are a strategic thinker who can collaborate to guide financial decision-making & reporting and elucidate considerations and recommendations grounded in financial analyses.

You will partner with the Accounting Team during the month-end close process to ensure that accrual and expenses are recorded accurately and promptly. Further, you will partner with Procurement, the Corporate Development and Strategy Team and our Portfolio and Program Management Team to further enhance internal operations and support important decisions regarding cash and portfolio management. You will work on multiple high impact finance projects for, and in partnership with, insitro's Executive Team and the Finance Leadership Team.

The opportunities for this role grow rapidly as our pipeline continues to progress. This is an exciting time to join and we are eager to find the right partner to, in a dynamic fashion, ensure our financial processes continue to support the needs of our rapidly changing organization. This is an onsite role that will operate 40% remotely. You will report to the Director, Corporate & Strategic Finance & FP&A.

Your Primary Responsibilities Include:

Budget and Forecast Planning

  • Lead the annual budget and forecasting process across all departments, inclusive of the latest estimate (LE) re-forecast to refine expectations for the year
  • Build models to analyze liquidity, cash concentration and cash forecasting
  • Prepare financial budget and results Board presentations
  • Prepare financial models to support operational initiatives and contemplated high dollar purchases

Financial Reporting & Variance Analyses

  • Lead and present month-end financial close results deck
  • Provide regular reporting and variance analyses to all departments to promote decision-making and alignment to our corporate objectives & identify opportunities for cost efficiencies
  • Understand insitro's business model so that Finance's commentary goes beyond numbers and contextualizes data with business outcomes
  • Partner with the Accounting Team on close processes around accruals and expenses, project code reporting and department and expense account reclasses
  • Prepare monthly headcount tracking and forecasting for executive review


  • Partner with Senior Leadership to evolve our capital allocation strategy and project level planning
  • Create build vs. buy analyses for potential external services & CapEx requests
  • Participate in special projects

System Enhancements, Process Improvement & Leadership

  • Lead Anaplan system enhancements, issue resolution and cost center manager system access to ensure important partners have access to their dashboards and data to support their decision-making
  • Continue to provide analytical support and suggestions regarding the implementation of planning systems and associated outputs; ensure Anaplan continues to meet the needs of our scaling organization
  • Review purchase requisitions to ensure budget and financial compliance
  • Contribute to continuous process improvements to identify opportunities to streamline and eliminate redundancies
  • When applicable, hire and mentor a team to support company growth

You will join an exciting biotech startup that has long-term stability due to significant funding, while maintaining a culture of innovation. You will work as part of a close-knit team, learn career enhancing skills, and help shape insitro's culture, strategic direction, and overall impact!

About You

  • Bachelor's degree in Business, Finance, Accounting or related field
  • 8+ years of relevant work experience in the biotech life sciences sector with a combination of private and public companies
  • MBA, CFA, CPA certification or consulting experience highly preferred
  • Experience working in Anaplan and Oracle Cloud or equivalent systems
  • Exceptional financial modeling (including clinical trial modeling), reporting metrics and presentation in Excel, Thinkcell, G-Sheets and G-Slides
  • Excellent communication & strong interpersonal skills
  • Excellent project management skills and the ability to collaborate cross-functionally
  • Ability to translate data into concrete recommendations and actions

Your Ways of Working and Alignment with insitro Values

  • "Get Things Done": A self-starter who can prioritize and advance multiple projects under the resource, information and time constraints of an early stage startup
  • "Engage with Respect": Prioritize a compassionate understanding of the needs and perspectives of insitro teams & leaders in every interaction and analysis
  • "Own the Outcome": Proactively take ownership of solving problems
  • Passion for making a difference in the world!

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $185,000 - $200,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, insitro also provides our employees:

  • 401(k) plan with employer matching for contributions
  • Excellent medical, dental, and vision coverage (insitro pays 100% of premiums for employees on our base plans), as well as mental health and well-being support
  • Open, flexible vacation policy
  • Paid parental leave
  • Quarterly budget for books and online courses for self-development
  • Support to attend professional conferences that are meaningful to your career growth and role's responsibilities
  • New hire stipend for home office setup
  • Monthly cell phone & internet stipend
  • Access to free onsite baristas and cafe with daily lunch and breakfast
  • Access to free onsite fitness center
  • Commuter benefits

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.



About insitro
insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit

Apply for this Job

* Required
resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in insitro’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Enter the verification code sent to to confirm you are not a robot, then submit your application.

This application was flagged as potential bot traffic. To resubmit your application, turn off any VPNs, clear the browser's cache and cookies, or try another browser. If you still can't submit it, contact our support team through the help center.