The Dowstream Processing group is an integral part of the company, which interacts with multiple teams, particularly Engineering, Protein Discovery, Analytics, Strain Development, and Fermentation. We are looking for a full time research associate or senior research associate with a strong background in protein biochemistry, protein purification, and protein analytics. This is a hands-on bench position that will juggle both individual and collaborative projects.

 

Essential Duties And Responsibilities

  • Develop commercial protein isolation processes from new production organisms at lab-scale. Facilitate tech transfer to pilot-scale
  • Collaborate with pilot engineers to design and execute scale-up and scale-down experiments to further optimize the processes
  • Troubleshoot and develop scale-down models for existing commercial processes
  • Characterize the DNA and protein content of new production organisms
  • Optimize final formulation and perform shelf life studies
  • Develop new methods, design and execute experiments, and interpret results
  • Maintain an accurate and up to date electronic lab notebook
  • Formal presentations to other team members every 3 months
  • Other duties as assigned

Education And/Or Experience

  • BS, or MS in Biochemistry, Biology, Chemistry, or related fields with 2+ years of industrial or academic laboratory experience post graduation.
  • Extensive protein purification experience.
  • Experience working with different types of resins.
  • Proficient in writing methods and executing runs on Akta FPLC using Unicorn software. Experience in column packing is a plus.
  • Proficient in total protein assays, SDS-PAGE, western blot, and UV-vis analysis.Mass spec experience is a plus.
  • Experience executing complex experiments with multiple variables and a high number of samples.
  • Experience in tangential flow filtration is a plus.

Language, Mathematical, And/OR Reasoning Ability

  • Hard working self-motivated individual with excellent quantitative skills, good organization and record-keeping skills.
  • Ability to juggle multiple projects and meet deadlines.
  • Strong oral and written communication skills
  • Attention to detail, fast learner, and ability to work well with interdisciplinary teams.
  • Ability to persevere through obstacles through determination and teamwork.
  • Creative and strong problem solving ability
  • Proficient in excel. Additional programming skills is a plus.
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