What if…you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?
Apriori Bio is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for Global Pathogen Shield™ protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats. The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&D platform.
Apriori Bio is a product of Flagship Pioneering's venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.
Position Summary:
This is an exciting opportunity for a dynamic and collaborative Scientist to join us in our mission to develop next generation vaccines! We are looking for someone to build novel and robust med- to high-throughput screening systems and assays that generate data to inform immunogen design. The successful candidate will collaborate closely with project teams to drive innovative approaches and solutions. The scope of this work will include not only technology development and scaling, but the organization and tracking of (bio)samples and high-dimensional data throughout complex experimental pipelines. Expertise in yeast surface display, high-throughput screening, and/or flow cytometry / FACS is required, and general experience with antibody characterization, immune profiling, and/or protein engineering platforms would be beneficial.
Key Responsibilities:
- Work closely with other experimental and computational scientists to design, optimize, and implement innovative screening platforms
- Build a robust infrastructure of laboratory protocols, tools, and systems that will scale efficiently
- Optimize screening workflows using experimental scaling and automation
- Produce and track high-dimensional datasets
- Train and mentor research associates
- Help formulate and articulate the company’s scientific and technical strategy, and monitor progress toward key strategic goals on an ongoing basis
- Communicate progress, insights, and conclusions to colleagues in scientific and leadership meetings
- Collaborate with computational scientists to develop efficient analytical pipelines, guide data analysis, interpret results, and build an iterative experimental cycle
Basic Qualifications:
- Education and training in molecular or cellular biology, biochemistry, or immunology:
- PhD and 2+ years of relevant experience, or
- BSc/ MS and 8+ years of relevant industry experience
- Technical expertise:
- flow cytometry/ FACS
- high-throughput screening, yeast surface display, deep mutational scanning
- liquid handlers and lab automation
- Demonstrated post-PhD experience in using and scaling innovative high-throughput assays and tools
- Strong communication, organization, and interpersonal skills
- Detail-oriented, entrepreneurial, and adaptable to dynamic environments
- Some mentoring/ management experience
Preferred Qualifications:
- Experience with antibody characterization, immune profiling, protein engineering, or antigen design is a plus
- Familiarity with generating DNA libraries, high-throughput cloning and molecular biology, and/or NGS
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
