What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

FL94 Inc., is a privately held, early-stage biotechnology company pioneering Protein Editing. At FL94 we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of novel chemistry modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with machine learning to enable generative design of protein editing chemistries. FL94 is backed by Flagship Pioneering, bringing the courage, vision, and resources to guide FL94 from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! 

Position Summary:

FL94 is seeking an experienced, creative, and talented Senior Scientist of compound management and characterization to join our research team. In this role you will be operating at a critical node between internal and external compound logistics, formatting, data generation and management, discovery chemistry and biology, and compound properties assessments.  Key to the success of the entire research organization is the establishment of robust and rapid compound management processes to impact programs at all points of the discovery continuum.

Successful candidates will be able to thrive in a fast-paced, action-oriented, team environment and display a clear passion for science and impact. The individual will have demonstrated evidence of technical expertise and experience overcoming challenges and moving projects forward with urgency.  Experience guiding junior scientists technically and strategically will be important.  They will be interested in from the lab and be dedicated to scientific development of themselves and their team.

Key Responsibilities:

  • Implement hardware and software to build a current state of the art compound management based on the SPT Labtech comPOUND platform
  • Establish optimal workflows (processes and automation) to expedite compound formatting and availability to internal customers
  • Coordinate with internal and external chemistry to ensure timely entries into internal workflows
  • Generate high quality compound characterization data (e.g., solubility, chromeLogD…) for ML encoding and therapeutic discovery
  • Operate as the functional program/department lead across multiple domains of program leadership and management
  • Ensure rapid and accurate turnaround of data, to agreed timelines, to drive achievement of key project goals
  • Translate experimental data into meaningful insights and present the analyzed data in team meetings


  • PhD in with 3+ years practical experience or BS with 7+ years’ experience in pharma-grade small molecule drug discovery with strong background in chemistry and/or biochemistry.
  • Hands on experience with modern automation hardware specific to compound formatting and assay execution
  • Experience with compound registration, assay data management… with preference for Dotmatics-based platforms
  • Experience with plate-based assays for compound properties characterization a preferred but not required skill set for all applicants
  • Ability to engage and perform in a multifunctional environment as a leader by example, reliable teammate, and a can-do attitude.
  • Clear communicator using various mediums (direct communication, team presentation…) that inspires teammates and raises the bar on innovation, creativity, and a sense of urgency

Location: Cambridge, MA

More About Flagship Pioneering

Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $100 billion in aggregate value. To date, Flagship has deployed over $3.1 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises  transformative companies, including  Moderna (NASDAQ: MRNA), Sana Biotechnology (NASDAQ: SANA), Seres Therapeutics (NASDAQ: MCRB), Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Generate Biomedicines, Tessera Tx, and others.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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