Mass Spectrometry Associate Scientist/Scientist


Vesalius Therapeutics is seeking a talented Research Associate Scientist / Scientist with broad expertise in mass spectrometry to enable our drug discovery programs. As a part of the Assays & HTS team, you will use a range of assay technologies for high and moderate throughput testing of small molecules to support several portfolio projects.

In this role, you will be an essential part of an interdisciplinary team of highly creative and talented individuals who create and apply these assays. You will use state-of-the-art technologies to enhance the throughput and physiological relevance of assays and advancement of novel therapeutics targeting newly identified disease pathways. To succeed, you will be a collaborative team player who thrives in a dynamic, fast-paced environment.


What You’ll Do:

  • Establish mass spectrometry-based capabilities to measure proteins, lipids, and other biomolecules to enable a diverse portfolio of projects
  • Independently conceptualize, design, and perform experiments using high resolution mass spectrometry and related bioinformatic tools
  • Perform metabolic profiling of patient-derived cells and profiling of compound activities
  • Oversee operation and management of mass spectrometry (MS) lab instrumentation


What You’ll Bring:

  • B.S. in molecular biology or related discipline + 4 years of experience (preferably in industry), or MS degree + 10 years and/or equivalent experience
  • Knowledge of experimental design
  • Extensive experience with modern state-of-the art high resolution mass spectrometers (nanoLC-MS, analytical LC-MS, and MALDI systems)
  • Ability to efficiently troubleshoot MS systems and quickly adapt to a diverse portfolio of projects, evolving technology and assay methodologies
  • Familiarity with MS bioinformatic software (e.g., Proteome Discoverer, Protein Metrics, BioPharma Finder, PEAKS, etc.) and establish data infrastructure for MS data through coordinated effort with data informatics team
  • Demonstrated ability to work in a dynamic environment as a team player with a strong work ethic, excellent communication abilities and time management skills
  • Curiosity and willingness to ask questions and seek clarity
  • Ability to work both independently and collaboratively
  • A track record of scientific vigor and creativity in carrying out research


What We’ll Offer You: 

  • Comprehensive, competitive healthcare (PPO) and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, three weeks’ paid time off with additional holidays, 401k retirement plan, disability and life insurance, and commuter benefits. 
  • A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team. 
  • Participate in the development and growth of a company with enormous potential impact on human health
  • Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things. 


Who We Are:  

Vesalius Therapeutics is a Flagship Pioneering platform company with a bold and critical mission to revolutionize drug development for the diseases that cause 90% of global morbidity and mortality.   

The company was founded in 2019 in Flagship Labs, Flagship Pioneering’s innovation foundry.  Vesalius is led by CEO Christopher Austin, M.D., Flagship Managing Partner, Doug Cole, M.D., and a leadership team with decades of experience working at some of the most renowned pharma and biotech companies in the industry. 

Vesalius’s ContinuumDiscovery™ platform harnesses a combination of human clinical data and genetics, artificial intelligence and machine learning, and patient-derived experimental models into a uniquely potent discovery engine.  

You can read more about our mission here. 

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