Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.
Position Summary:
The Scientist will lead our efforts to optimize novel gene writing technologies to support the downstream development of innovative therapeutics. This is a highly visible role that is cross-functional to bridge basic biological research and translational applications of Gene Writing. We are searching for a driven, enthusiastic and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.
Key Responsibilities:
- Optimize and validate non-viral gene delivery of novel gene writing tools to modify human T cells
- Contribute to all different stages of the program from inception, in vitro optimization, leading the identification of next generation RNA writer, and its characterization
- Manage and train junior research associates
- Collaborate with internal and external research teams to advance our leading candidates of Gene writing technologies
Basic Qualifications:
- MS with 6+ in an academic or industry setting or Ph.D. in biological sciences
- Hands-on experience in assays that are crucial for characterization of T cell biology and function
- Proficiency with multi-color flow cytometry
- Proficiency in non-viral or viral gene delivery into T cells
- Creative problem-solving skills
- Strong written and oral communication skills
- Strong interpersonal skills, and ability to effectively work as part of a collaborative team
Preferred Qualifications:
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- Experience in the research of immunology
- Experience of current gene editing technologies, preferred but not limited to CRISPR and AAV
- Experience in leading projects and mentoring junior reports
- High throughput screening
More About Flagship Pioneering
Flagship Pioneering has conceived of and created companies such as Moderna Therapeutics (NASDAQ: MRNA), Editas Medicine (NASDAQ: EDIT), Omega Therapeutics (NASDAQ: OMGA), Seres Therapeutics (NASDAQ: MCRB), and Indigo Agriculture. Since its launch in 2000, Flagship has applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
