Company Summary:

FL74, Inc. is a privately held early-stage company that is harnessing the power of machine learning and artificial intelligence (AI) to discover biological and technological insights from heterogenous data and transform the way we generate the next wave of breakthrough opportunities in human health and sustainability.

FL74 was founded by Flagship Pioneering, an innovation enterprise dedicated to originating and developing first-in-category life sciences companies. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. These companies include Moderna Therapeutics, Rubius Therapeutics, Evelo Biosciences, and Indigo Agriculture.

Position Summary:

We are seeking a machine learning scientist with experience developing and applying Deep Learning (DL) models for problems and datasets in the biological (life sciences) domain.  Candidate will help design, implement and analyze DL models for biological applications and ideate with a multi-disciplinary and cross-functional team to drive the development of a state-of-the-art AI engine for applications in human health and sustainability.  This is an exciting opportunity to be part of a fast-paced, highly dynamic entrepreneurial environment.

Key Responsibilities:

  • Work with FL74 team to develop and apply ML and DL models for biological applications
  • Study heterogenous internal and external datasets to address questions critical to FL74’s core objectives and generate testable hypotheses.
  • Design, plan, and execute experiments that support model validation and platform development
  • Develop clear, intuitive visualizations. Communicate analysis results via presentations to a multi-disciplinary audience
  • Cultivate a data-centric and process-oriented company philosophy by creating and maintaining best practices for software development, data management, and infrastructure
  • Monitor and evaluate new and emerging technologies and models and identify opportunities for collaboration within Flagship Pioneering companies, academia, and third-parties.

Basic Requirements:

  • PhD or equivalent level of experience in developing and applying machine learning (ML) methods or models to experimental data. Experience in systems/network biology, transcriptomics, genomics, biophysics or neuroscience data is a strong plus. PhD may be in (1) a field directly relevant to ML (e.g. Machine Learning, Statistics, Computer Science, Mathematics) or (2) natural sciences (e.g. Physics, Computational Biology/Chemistry, Biology).
  • Fluency in Python and standard ML tools and packages (e.g. Deep Graph Library, PyTorch, Snorkel, etc.)
  • Familiarity with AWS, GCP, or similar cloud-computing services
  • Motivated and team oriented, with an ability to thrive in an entrepreneurial and multidisciplinary environment.
  • Ability to independently lead and run research projects, while maintaining close communication with team members
  • Excellent communication and presentation skills. Must be able to speak and ideate with multi-disciplinary team including biologists.  Must be able to think independently, work collaboratively and contribute to an active intellectual environment.

Preferred Requirements:

  • Experience in one or more of the following areas/topics: modern neural network architectures (graph NNs, Transformers, etc.), variational methods, GANs, Gaussian processes
  • Familiarity with containerization and task orchestration tools (e.g. Docker, Kubernetes, Slurm)
  • Experience working with major biological databases and datasets (e.g. TCGA) is a strong plus


Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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