Company Summary:

Serqet Therapeutics is one of the latest companies founded through Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics, Rubius Therapeutics, and Evelo Therapeutics were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $19+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. Serqet Therapeutics is integrating the latest developments in computational and experimental biology to discover novel therapeutics for a broad range of diseases.

Position Summary:

This position will lead a High Throughput Screening (HTS) team with the goal of discovering new small molecule drug candidates and assisting with small molecule optimization.


  • Develop a team focused on high throughput approaches
  • Lead, design and execute different assay models
  • Provide scientific leadership by coordinating activities with teams across different functional areas
  • Data processing and management
  • In depth understanding of the drug discovery and development process
  • Extensive hands-on experience running small molecule, biologic, or cell-based screens
  • Compound inventory and distribution
  • HTS and robotics & chemical library management
  • Maintaining an orderly and safe work environment
  • Using good judgement, take appropriate precautions and follow prescribed safety measures ensuring safety
  • Define assay parameters & optimize protocols


  • PhD+ 7 years relevant experience
  • MS+12 years industry experience or equivalent in cell biology, biochemistry, molecular biology, or related field
  • In depth expertise with cellular and biochemical assays and applications to high throughput screening
  • In depth experience with characterizing nucleic acid modalities in cell and cell free assays utilizing various transfection and electroporation techniques
  • Experience with translational RNA assays and characterization of mRNA is desired
  • Experience in the application of automation tools to HTP assays is desired
  • 5-10 years of experience developing technology platforms for therapeutic programs in industry
  • Experience with developing strategic timelines and executing successful on corporate goals
  • Demonstrated ability in working with highly skilled teams in a fast-paced, entrepreneurial, and technical environment
  • Strong management experience and success in developing a scientific team and program
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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