Company Summary:

Laronde is an early-stage biotechnology company with the mission to become the leader in the development of nucleic acid medicines by leveraging its multi-modality eRNA platform. Our modular Endless RNA™ (eRNA) platform, will be supported by a large-scale digital and manufacturing infrastructure with the bold vision of 100 new medicines within the next decade. With eRNA, we’re making new therapeutics that will become essential medicines of the future to address unmet needs across multiple disease areas. Check out www.laronde.bio for more information on our vision.

Laronde was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources and grows first-in-category life sciences companies. Since 2000, Flagship has created over 100 groundbreaking companies pioneering novel and proprietary biological, industrial and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna Therapeutics (MRNA), Seres Therapeutics (MCRB), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Evelo Biosciences (EVLO), Kaleido Biosciences (KLDO) and Indigo Agriculture.

Position Summary:

We are looking for a Senior Research Associate who brings enthusiasm, scientific rigor and a desire to perform in vivo pharmacology studies for the development novel eRNA therapies. 

Key Responsibilities: 

  • Contribute to study design, planning and performing in vivo studies related to pharmacokinetic, pharmacodynamic and efficacy studies from early exploratory to IND stage
  • Work both independently and as part of a collaborative team to:
    • execute in vivo studies internally and coordinate externally (CRO, academic lab)
    • analyze in vivo experiments and present experimental findings
    • perform various in vitro / ex vivo analyses in generated animal samples
    • author study reports 
  • Maintain detailed records of experimental protocols and data in electronic laboratory notebook in accordance with company policy
  • Additional duties and responsibilities as required

REQUIREMENTS

  • BS or MS in pharmacology, animal science or related discipline
  • 4 or more years of relevant in vivo experience 
  • Strong rodent animal handling skills and hands-on in vivo pharmacology skills, including dosing (IV, SQ, IP and ID), preparation of test compounds, anesthesia, necropsy, blood and tissue collection for PK and PD biomarker analysis and efficacy
  • Skilled in small animal surgery preferred
  • Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner
  • Strong presence, sense of urgency and priorities as well as flexibility in working schedule to accommodate weekend work
 
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
 
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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