Company Summary:

Tessera Therapeutics is an early-stage life sciences company pioneering Gene Writing, a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

Position Summary:

We are building a new unit for high-throughput cell screening using iPSCs and iPSC-derived hepatocytes. The scientist will be responsible for tissue culture and quality control for iPSCs and hepatocyte differentiation. This individual will design experiments, run assays, including but not limited to PCR, immunocytochemistry and flow cytometry. We are searching for a driven, enthusiastic and self-motivated individual who has strong organization skills and pays attention to details. This individual will join a dynamic, rapidly growing, and highly collaborative team.

Key Responsibilities:

The successful candidate will work both independently and as part of a collaborative team to:

  • Culture and conduct quality control for iPSCs
  • Differentiate, maintain, and benchmark iPSC-derived hepatocytes
  • Run assays, including but not limited to PCR, immunocytochemistry/high content imaging, and flow cytometry
  • Make detailed observations, analyze data, and make logical and data-driven conclusions
  • Keep good records of experiments and cell line inventory
  • Prepare technical reports, summaries, protocols, and quantitative analyses
  • Collaborate with various groups and present data at meetings

Basic Qualifications:

  • Ph.D. in cell biology or related fields.
  • Experience with culturing human iPSCs/ESCs
  • Excellent troubleshooting and capability, attention to detail and ability to work independently
  • Excellent communication and presentation skills
  • Excellent organization, record-keeping, and time management skills
  • Team oriented and self-motivated

Preferred Qualifications:

  • Experience with differentiating human iPSCs/ESCs into any cell type
  • Experience with differentiating human iPSCs/ESCs into hepatocytes is highly desirable
  • Past experience with tissue culture automation and/or flow cytometry


More About Flagship Pioneering

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has, through its Flagship Labs unit, applied its unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $50B in aggregate value. To date, Flagship has deployed over $2.2B in capital toward the founding and growth of its pioneering companies alongside more than $18B of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Foghorn Therapeutics (NASDAQ: FHTX), Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Sigilon Therapeutics (NASDAQ: SGTX).

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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