Company Summary:

FL74, Inc. is a privately held early-stage company that is harnessing the power of machine learning and artificial intelligence (AI) to discover biological and technological insights from heterogenous data and transform the way we generate the next wave of breakthrough opportunities in human health and sustainability.

FL74 was founded by Flagship Pioneering, an innovation enterprise dedicated to originating and developing first-in-category life sciences companies. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. These companies include Moderna Therapeutics, Rubius Therapeutics, Evelo Biosciences, and Indigo Agriculture.

Position Summary:

We are seeking a quantitative or computational biologist with experience modeling and analyzing biological systems and a strong background in deep learning (DL) tools and techniques.  This scientist will apply DL tools and methods to model and conduct analyses on multiple types of biological data.  They will also ideate with a multi-disciplinary and cross-functional team to drive the development of a state-of-the-art AI engine.  This is an exciting opportunity to be part of a fast-paced, highly dynamic entrepreneurial environment.

Key Responsibilities:

  • Work with FL74 team to develop and apply novel ML models on heterogenous biological data
  • Study internal and external datasets to address questions critical to FL74’s core objectives and generate testable hypotheses.
  • Design, plan, and execute experiments that support model validation and platform development
  • Develop clear, intuitive visualizations. Communicate analysis results via presentations to a multi-disciplinary audience
  • Cultivate a data-centric and process-oriented company philosophy by helping to maintain best practices for software development, data management, and infrastructure
  • Monitor and evaluate new and emerging technologies and models and identify opportunities for collaboration within Flagship Pioneering companies, academia, and third-parties

Basic Requirements:

  • PhD or equivalent level of experience in quantitative or computational biology. Examples include system biology or immunology, synthetic biology, network biology, transcriptomics, genomics, biophysics, neuroscience or evolutionary dynamics.
  • Experience applying deep learning (DL) tools and techniques to model biological data and processes
  • Fluency in Python and standard ML tools and packages (e.g. Deep Graph Library, PyTorch, Snorkel, etc.)
  • Motivated and team oriented, with an ability to thrive in an entrepreneurial and multidisciplinary environment
  • Ability to independently lead and run research projects, while maintaining close communication with team members
  • Excellent communication and presentation skills. Must be able to speak and ideate with multi-disciplinary team including biologists.  Must be able to think independently, work collaboratively and contribute to an active intellectual environment

Preferred Requirements:

  • Experience in one or more of the following areas/topics: graph neural networks, NLP (e.g. LSTMs, Transformers), CNNs, variational methods or GANs
  • Familiarity with AWS, GCP, or similar cloud-computing services
  • Familiarity with containerization and task orchestration tools (e.g. Docker, Kubernetes, Slurm)
  • Experience working with reference biological databases and datasets (e.g. TCGA) is a strong plus


Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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