Company Summary:

Each day, the lives of more than 2 billion people across the globe are impacted by chronic diseases. Moreover, the economic burden on society of treating chronic disease is spinning out of control. Today, this dire situation appears unlikely to change as >95% of global healthcare costs are spent on treating rather than preventing chronic diseases. FL84, Inc. is a privately held early-stage company that is applying advanced biological and computational platforms to discover breakthroughs in detection of and intervention against the etiologies that drive progression from health to disease. Our goal is to leverage our proprietary platforms to disrupt the current approach of treating chronic disease too late. We endeavor to provide true health care rather than sick care to individuals that are at risk of progressing to disease.

FL84 was founded by Flagship Pioneering, an innovation enterprise dedicated to originating and developing first-in-category life sciences companies. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. Flagship-founded companies include Moderna Therapeutics, Rubius Therapeutics, Seres Therapeutics, Evelo Biosciences, and Indigo Agriculture.

Position Summary:

FL84 is seeking a highly motivated and experienced molecular biologist to join our early-stage biotech company. The successful candidate will be a driven, experienced scientist who is enthusiastic about leveraging state-of-the-art techniques, such as single-cell RNA sequencing and iPS cell-derived models, to help drive experiments that will unlock key insights underlying disease progression. An ideal candidate will pride themselves on their ability to craft scientifically logical stories out of complex data and convert them into executable experiments. The position will provide a unique opportunity to play a foundational role in the development of FL84’s preclinical platform.


  • Collaborate with FL84 scientific team to design and execute cell-based and molecular biology experiments to support key hypotheses
  • Develop laboratory protocols and optimize workflow to build platform capabilities
  • Troubleshoot / optimize preclinical assays as needed
  • Maintain scientific and technical expertise through familiarity with scientific literature
  • Coordinate with CROs and external collaborators to support advancement of projects
  • Communicate results to rest of FL84 team and executive management

Basic requirements:

  • PhD with 5+ years of experience in molecular biology, cell biology, or related fields
  • Deep knowledge of cell and molecular biology techniques
  • Experience in single cell RNA seq library preparation and sequencing
  • Understanding of NGS approaches and demonstrated ability to collaborate with computational biologists to design and optimize experiments
  • Experience establishing and maintaining mammalian cell cultures
  • Demonstrated ability to be a thoughtful contributor to experimental design and data analysis
  • Ability to work both independently and collaboratively in a team-oriented, fast-paced environment
  • Excellent oral and written communication skills
  • Highly attentive to detail, flexible, and curious

Preferred experience:

  • Experience working with a variety of biomaterials (tissues, blood, primary cells, etc.)
  • Demonstrated ability to design and implement iPSC experiments
  • Familiarity and experience conducting single cell RNA sequencing data analysis
  • Experience leading and managing laboratory team
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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