Company Summary:

What if…you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

Flagship Labs 77 (FL77) is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for Global Pathogen Shield™ protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats.  The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&D platform.

FL77 is a product of Flagship Pioneering’s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.

Position Summary:

We are seeking a Scientist or Senior Scientist with strong experience in virology and molecular biology to design and build innovative assays and perform a range of experiments focused on the development of novel health interventions. The ideal candidate will have a track record of success in inventing and deploying sophisticated new tools for high-volume, high-speed discovery, and deriving unique insights from biological data – particularly as regards protein structure, protein-protein interactions and immune system function.  Experience in immunology, virology and/or vaccine design is a strong plus.  An essential element of the role will be the ability to collaborate closely with other R&D scientists while adapting to and interpreting new experimental findings and providing experimental guidance in keeping with the company’s objectives.

Key Responsibilities:

Work closely with other molecular biologists and computational scientists within and beyond FL77 to design innovative, proprietary assays and perform critical data-generating experiments

Build an infrastructure of laboratory protocols, tools and systems to enable focused and rapid discovery and early pipeline development

Apply rigorous methods to interpret emerging data in the context of key scientific questions

Identify relevant external findings, tools and datasets, and build on these as necessary to support company objectives

Communicate insights and conclusions to the scientific team and executive management

Develop relationships with Flagship Pioneering’s broader science community and manage external consultants as needed

Ability to construct, maintain, troubleshoot viruses using state-of-the-art nonpathogenic virus model systems.

 

Minimum Qualifications:

Ph.D. or equivalent in molecular biology, cell biology, biochemistry, or a related field of biological science

Experience preparing virus (lentivirus, AAV, VSV…) for transgene expression

Experience in immunology, virology and/or vaccine design

Experience with viral infection and neutralization assays

Good understanding of evolutionary biology as pertaining to cellular and molecular systems

Cloning experience and familiarity with NGS/RNA-Seq methods

Experience with RNA isolation and reverse transcription

Experience with mammalian cell culture

Demonstrated post-PhD experience developing and using high-volume innovative assays and tools for biological discovery and to solve biological challenges

 

Preferred Qualifications:

Experience with directed mutagenesis strongly preferred

Experience working under BSL2 conditions strongly preferred

Previous work with biological sequence or protein structure datasets

Familiarity with biological data repositories and public omics data resources

 

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

 

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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