Company Summary:

What if…you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

Flagship Labs 77 (FL77) is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for Global Pathogen Shield™ protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats.  The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&D platform.

FL77 is a product of Flagship Pioneering’s venture creation engine, which has also given rise to companies such as Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), and Editas Medicines (NASDAQ: EDIT). Since Flagship’s founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.

Position Summary:

We are seeking a Senior Scientist with experience in computational biology and machine learning to design data infrastructure and models for biological discovery and the development of novel health interventions. The ideal candidate will have experience deriving insights from biological data through machine learning – particularly as regards protein structure, NGS sequencing and/or phylogenetics. Experience in immunology, virology and/or vaccine design is a plus.  An essential element of the role will be the ability to collaborate closely with other R&D scientists while adapting to and interpreting new experimental findings and providing experimental guidance in keeping with the company’s objectives.

Key Responsibilities:

  • Work closely with molecular biologists and other computational scientists within and beyond FL77 to design data-generating experiments for effective modeling
  • Build computational infrastructure to process and analyze NGS and other datasets
  • Design and deploy machine learning models
  • Develop and apply statistical methods to interpret emerging data in the context of key scientific questions
  • Identify relevant external datasets and repurpose as necessary to support company objectives
  • Communicate insights and conclusions to the scientific team and executive management
  • Develop relationships with Flagship Pioneering’s data science community and manage external consultants as needed

Minimum Qualifications:

  • Ph.D. or equivalent in computational biology, computer science, mathematics, or a related field
  • Deep understanding of molecular and evolutionary biology
  • Programming ability (e.g. R, Python, Julia) and knowledge of best practices
  • Machine learning experience including feature engineering and model introspection
  • Familiarity with biological data repositories and public omics data resources
  • Demonstrated post-PhD experience using computational biology and/or machine learning approaches to solve biological challenges

Preferred Qualifications:

  • Experience with distributed or cloud computing
  • Previous work with biological sequence or protein structure datasets
  • Experience in immunology, virology and/or vaccine design

Values and Behaviors

Flagship is an experiment in institutional, entrepreneurial, innovation practiced in the context of a small company with an insurgent mindset.   We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment.  The level of the role will commensurate with the education and years of experience of the identified candidate.



Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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