Company Summary:

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of gene therapy by exploiting a family of naturally occurring commensal viruses to create the first redosable and targetable DNA medicines. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need.

Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna (MRNA), Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health (AXLA), Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

The Research Associate will be responsible for performing a variety of laboratory procedures related to protein purification process and analytical development. This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biologic drug discovery experience with pioneering discoveries driving a novel biological platform.

Key Responsibilities:

  • Familiarity with basic laboratory procedures including pipetting and aseptic technique.
  • Perform various bench scale procedures including buffer and media preparation, centrifugation and filtration.
  • Perform lab scale protein purification procedures using standard chromatographic techniques and equipment.
  • Participate in experimental design and optimization.
  • Perform various analytical procedures needed to support purification activities. This includes SDS-PAGE, western blotting, and HPLC. Perform data analysis as needed.
  • Familiarity with depth filtration, TFF, and UF/DF of protein solutions.
  • Participate in scale-up of developed processes and ultimate transfer to manufacturing.
  • Participate on multi-disciplinary teams and communicate results (i.e., presentations, writing reports).

Preferred Qualifications:

  • Basic knowledge and application of theories, principles and techniques in protein purification and characterization.
  • Experience working with recombinant proteins and performing various analytical techniques such as HPLC and SDS-PAGE is preferred.
  • Familiarity with cell culture techniques and procedures and molecular biology procedures such as qPCR and southern blotting is a plus. 

Basic Qualifications:

  • BS, MS or equivalent in a science program preferred (e.g. biology, chemistry, etc.)
  • 2-5 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings.
  • Attention to detail and problem-solving skills.
  • Motivated, curious, and comfortable working with highly technical projects and personnel.
  • Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.
  • Comfortable delivering against challenging commitments.
  • Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment.

 

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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