Flagship Labs 63 Inc. (FL63) is a privately held, well-funded, early-stage platform biotechnology company that is leveraging emerging insights in RNA biology to develop novel human therapeutics with a focus on mRNA translation and post-transcriptional RNA modifications.

FL63 was founded by Flagship Pioneering, an innovation enterprise that conceives, resources and grows first-in-category life science companies. The firm’s institutional innovation foundry, Flagship VentureLabs, is where teams of scientific entrepreneurs systematically evolve ideas and turn previously undiscovered areas of science into real-world ventures. Flagship manages >$2.4B in funds and has applied its hypothesis-driven innovation process to foster 75 scientific enterprises. These companies represent >$19B in aggregate value, have been issued 500+ patents, and have conducted >50 clinical trials for novel therapeutic agents. Flagship’s portfolio companies include Seres Therapeutics, Rubius Therapeutics, Moderna, Syros Pharmaceuticals, Axcella Health, Evelo Biosciences and Indigo Agriculture.

FL63 is a highly dynamic, entrepreneurial and innovation-driven organization seeking to hire an exceptional scientist to join our growing team. A successful candidate will have a Ph.D. in cell/molecular biology (or equivalent), an additional 3-5 years of relevant experience, and a proven track-record of scientific excellence as evidenced by a strong publication and/or patent record. The candidate’s career goals, laboratory skills, and core competencies should be aligned with the description below.

Key Outcomes:

  1. Design, execute, and interpret multiple experimental workflows with an emphasis on RNA-centric next generation sequencing (NGS) assays.
  2. Internalize and develop novel NGS technologies related to the company’s mission.
  3. Continually cultivate scientific/technical expertise through critical review of the scientific literature, attending external conferences, and developing relationships with key opinion leaders.
  4. Work effectively with a cross-functional biology, technology, and chemistry team to contribute to the vision, strategy, and tactics of the organization.
  5. Willing to work hands-on in the wet lab for the first 1-3 years and to recruit/develop a team in 2-5 years.

Required Skills:

  1. Strong general molecular biology background
  2. Mastery in one or more next generation sequencing platforms (i.e. Illumina, Nanopore) with a deep knowledge of RNA-centric NGS methods including RNA-seq, Ribo-seq, eCLIP, RNA chemical probing (i.e. SHAPE-MaP, DMS-MaP-seq) or equivalent
  3. Proven track record in novel RNA-centric NGS method development
  4. Experience in targeted gene expression profiling techniques (e.g. qPCR, bDNA)
  5. Working knowledge in relevant statistical and bioinformatics methods (e.g. R, Python) to enable effective collaboration with computation biology team
  6. Excellence in experimental design and execution

Preferred Skills:

  1. Established track record in the RNA biology field
  2. Experience with viability- and FACS-based pooled shRNA/CRISPR screening and other massively parallel assay formats
  3. Established track record in people management and team leadership skills

Core Competencies:

  1. Fast-acting/efficient. Moves quickly and proactively with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key priorities. Demonstrates tenacity and willingness to go the distance to get something done.
  2. Integrity. Does not cut corners ethically. Earns trust and maintains confidences. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Follows-through on commitments. Expects a high level of personal performance and team performance.
  3. Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and independently achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw insightful conclusions.
  4. Creativity & Innovation. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation.
  5. Teamwork. Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions.
  6. Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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