Company Summary:
FL60 is one of the latest companies founded through Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics, Rubius Therapeutics, and Evelo Therapeutics were conceived and created. Since Flagship’s founding in 2000, the firm has originated and fostered the development of nearly 100 scientific ventures resulting in $19+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. FL60 is integrating the latest developments in experimental biology to discover novel therapeutic strategies for a broad range of CNS disorders.
Position Summary:
We are seeking a highly motivated Research Associate to join our early target discovery team. You will play a hands-on role in a highly collaborative and dynamic group that develops and implements processes to differentiate and characterize iPSC cellular models at an industrial scale. The team will utilize these models for high-throughput phenotypic and multi-omic assays to uncover new human genetic associations and identify new targets in a broad range of CNS disorders. Excellent communication, record-keeping, and teamwork will be critical.
Key Responsibilities:
  • Maintain human pluripotent stem cells (hPSCs).
  • Generate neural subtypes from hPSCs.
  • Establish cellular and biochemical assays for screening and target validation.
  • Analyze, interpret, and communicate scientific data.

Minimum requirements:

  • BS or MS degree or equivalent in neuroscience, cell biology, biochemistry, or a similar discipline. 0 - 2 years of Industry or Academic Lab research experience, preferred.
  • Experience in working with human iPS / ES cells is strongly preferred.
  • Proficiency in basic laboratory techniques such as qRT-PCR, western blotting, cloning, immunostaining, lentiviral production, ELISA, and flow-cytometry.Familiarity with lab automation solutions.
  • Ability to work productively in a fast-paced environment that requires a high level of communication, collaboration, and organization.

Highly desirable:

  • Experience in molecular biology techniques including genome engineering.
  • Experience in developing cell-based functional assays, including high-content imaging and/or live-cell imaging.


Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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