Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a new member of the Revolution Medicines team, the Director, Medical Project Management will lead strategic and operational execution of Medical Affairs programs across multiple assets and lifecycle stages. This role will be critical in ensuring operational excellence, cross-functional coordination, and launch readiness for key initiatives that drive medical impact.

As a senior member of the Medical Operations function, the Director will serve as a central point of contact for program planning, delivery, and governance of critical Medical Affairs projects—spanning scientific communications, congress strategy, advisory boards, medical education, and post-marketing data generation.

Key responsibilities include:

Strategic Project Leadership

  • Lead cross-functional medical planning and execution for launch readiness, integrated evidence generation plans, scientific platform development, and field medical enablement.

  • Define and oversee medical workstreams for new product launches, indication expansions, and lifecycle management.

  • Serve as program lead for cross-functional medical workstreams, ensuring strategic alignment with Medical Affairs, Clinical Development, Regulatory, and Commercial goals.

Program Oversight & Governance

  • Establish and maintain program-level dashboards, KPIs, and governance frameworks to monitor progress, identify risks, and drive accountability.

  • Facilitate strategic reviews, cross-functional planning meetings, and Medical Affairs quarterly business reviews.

Cross-functional Collaboration

  • Partner closely with leaders in Field Medical, Medical Communications, Medical Information, HEOR, and Clinical Operations to ensure unified execution and prioritization.

  • Act as a trusted advisor to Medical Affairs leadership in shaping strategy, resourcing, and long-range planning.

Operational Infrastructure & Process Excellence

  • Drive the evolution of Medical Affairs operations through process optimization, SOP development, and adoption of best practices.

  • Champion the implementation of medical planning tools and platforms, including Veeva Medical, Smartsheet, publication planning tools, and project dashboards.

Congress & External Engagement Readiness

  • Lead project management to support operational planning for major scientific congresses (e.g., ASCO, ESMO, AACR), including alignment across abstracts, symposia, and booth activities.

  • Oversee project management supporting coordination and execution of high-impact stakeholder engagements (ad boards, medical education programs, scientific exchange events).

Team Leadership & Vendor Management

  • Provide strategic oversight to project managers and contractors supporting Medical Affairs initiatives.

  • Manage relationships with key vendors and external partners to ensure high-quality, on-time, and on-budget delivery.

Required Skills, Experience and Education:

  • Bachelor’s (BS) degree required; advanced degree (MS, MBA, PharmD, PhD) or PMP certification preferred.

  • 15+ years of experience in biotechnology or pharmaceutical industry (with BS), 13+ years (with MS) or 11+ years (with PharmD/PhD), including 8+ years in Medical Affairs or biotechnology project or program management roles.

  • Strong understanding of the Medical Affairs function, including scientific communications, MSL engagement, medical congresses, and data dissemination.

  • Proven track record of leading large, cross-functional initiatives with significant visibility and complexity.

  • Highly skilled in influencing without authority, driving alignment, and fostering collaboration across functions and leadership levels.

  • Expertise in project governance, planning tools and operational frameworks.

  • Experience in oncology or precision medicine highly preferred.

  • Ability to work in fast-paced, matrixed environments and lead cross-functional initiatives.

  • Strong project management skills to oversee multiple priorities, timelines, and stakeholders effectively.

  • Excellent communication, interpersonal, and presentation skills to engage internal and external stakeholders effectively.

Preferred Skills:

  • Experience in precision oncology and targeted therapies.

  • Previous leadership in launch planning and medical communications/publications strategy.

  • Familiarity with digital tools and innovative solutions for medical communication.

The base salary range for this full-time position is $204,000 to $255,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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