Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Director, Patient Reported Outcomes is responsible for leading the strategy and execution Patient Reported Outcomes (PROs) strategies, plans and activities related to all Revolution medicines assets. The will be accountable to working across the development, medical affairs and commercial matrix to ensure PROs support the critical priorities of Revmed products. They must engage internally with a broad matrix but also will have to engage with regulators, providers and patients to design and implement the most appropriate programs to ensure robust evaluation of patient outcomes. Reporting to the VP, HEOR and RWE, this role will sit on their leadership team and provide input into the broader remit of the group. This is an exceptional opportunity to contribute to the advancement of healthcare by providing evidence that can shape the future of patient care in Oncology.

  • Implements optimal PRO strategy including managing research to support the selection, development and validation of measures.

  • Maximizes the impact of evidence of treatment benefit by providing input to briefing packages, publication strategies, and market access strategy.

  • Acts as an ambassador and promote the importance of PROs role to quantitative and qualitative COA across senior leadership.

  • Demonstrates leadership for PRO strategy with a strong influence across the Revmed leadership matrix.

  • Prepares relevant sections of documents and communications for regulatory agency meetings, support and/or participate in said meetings at regulatory agencies, and provide robust evidence in support of submission activities.

  • Supports dissemination of results from clinical trials as well asPRO development and validation studies that are aligned with publication strategy.

  • Participates in global external collaborations regarding policies, standards, and use of measures (e.g., PRO Consortium, BIO PFDD Task Force, EuroQol Group, ISPOR working groups).

  • Participates in creating and delivering education on measures for internal business partners.

  • Assists operations staff in securing licenses and commissioning translations/adaptations for instruments in a timely manner.

Required Skills, Experience and Education:

  • Experience with the application of PRO measures in hematology and oncology areas.

  • Experience conducting observational research involving PRO data collection and the interpretation and communication of results to key stakeholders.

  • Experienced with PRO requirements for regulatory and HTA/reimbursement agencies, including understanding of the FDA Patient-Reported Outcomes Guidance.

  • Knowledge of development and validation of COA measures.

  • Understanding of health care markets and regulatory and reimbursement decision making, especially in relation to the global use of PRO data.

  • Be abreast of rapidly changing methodological and regulatory environment.

  • Knowledge of the drug development process within hematology/oncology preferred.

  • Strong analytical and synthesis skills.

  • Demonstrated ability to understand and communicate with matrix teams.

Preferred Skills: 

  • Preference will be given to candidates with a Ph.D. or equivalent degree in a relevant discipline (e.g., psychology, psychometrics, outcomes research, public health) or those who possess a clinical doctorate (M.D., Pharm.D.) coupled with a master’s degree.

The base salary range for this full-time position is $236,000 to $295,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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