Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Playing a critical role as a lead statistician for oncology clinical studies and the subject matter expert (SME) in Biostatistics within Quantitative Sciences function, this position is to serve as a study-level lead statistician and provide statistical leadership and support for clinical development strategy and programs through product life cycle. 

  • Represent Biostatistics function on cross-function teams at study team and serve as a lead statistician for oncology studies.

  • Collaborate with various functions on study design and planning, protocol development, statistical analysis plan and analysis specifications.

  • Provide statistical support for study protocol development, analysis plan and specification through direct involvement and/or providing guidance to junior staff.

  • Plan and prepare independent data monitoring committee (DMC), coordinate with independent statistical data analysis center for DMC and study team for periodic DMC reviews.

  • Collaborate with data management and clinical operations over the course of clinical studies to provide statistical input to study conducts and database development as well as data collection and cleaning activities.

  • Collaborate with statistical programming to ensure that appropriate programs and documentations are being developed for datasets development and outputs generation, and ensure the statistical analyses specified in scientific protocols and/or analysis plans are conducted appropriately.

  • Provide statistical support for clinical publications, assist in data interpretation to ensure consistency and accuracy in data presentation.

  • Keep abreast in new developments in statistics, drug development, and regulatory guidance and share knowledge with functional and cross-functional team members.

Required Skills, Experience and Education:

  • Ph.D. or M.S. in Statistics/Biostatistics, minimum 4 years (for Ph.D.) and 6 years (for M.S.) of experience in biotech/pharma industry as a statistician. Level will be determined based on the relevance of experience.

  • Hands-on experience in design and analysis of oncology trials is a must.

  • Solid knowledge in ICH and other regulatory requirements related to biostatistical activities and clinical trials.

  • Excellent verbal and written communication skills are required.

  • Good interpersonal and project management skills are essential.

  • Proficiency in SAS and/or R.

Preferred Skills:

  • Hands-on experience in design and analysis of phase 3 oncology trials desirable.

The base salary range for this full-time position is $200,000 to $240,000 for candidates based at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the minimum and maximum salary for the position in Redwood City and will be adjusted for the local market a candidate is based. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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