As a word, Rapport describes relationships characterized by understanding, communication, teamwork, and trust. We reflect those qualities in our daily work, where we operate as one committed team that captures the collective knowledge and experience of all our members to maximally improve patients’ lives. And at a higher level we share an ambition and a passion to create impactful neuromedicines, with fewer side effects, that allow patients and their families to live healthier and more fulfilling lives.
On a molecular scale, our deep understanding of the intricate relationships between receptors, their associated proteins, and their distributions in specific cell types and brain regions enables us to precisely direct medicines to the neural circuits underlying disease pathophysiology.
We are seeking a skilled and highly motivated DMPK & bioanalytical scientist with a strong background in small molecules. This position is responsible for DMPK characterization and bioanalysis of pipeline compounds as they progress in clinical development.
Responsibilities:
- Be a SME for all DMPK and bioanalysis problem solving and conducting appropriate studies to support different stages of development.
- Identify CROs for all experimental conduct, define the scope, drive MSA and work orders
- Work closely with CROs and discovery DMPK to generate high quality data.
- Write summaries and reports for studies conducted externally, author and review summaries for regulatory submissions
- Present data at program team meetings & work closely with program leadership
- Work closely with QA to ensure compliance with all GLP activities
Qualifications:
- BS/MS degree with 12+ years, Ph.D. degree with 8-10+ years of relevant small molecule bioanalytical & DMPK experience.
- Must have significant experience with LC/MS/MS method development and validation in a GLP environment; hands-on experience with these activities at some point in the career is required
- Familiarity with DMPK assays (e.g. enzyme inhibition, induction, metabolite identification, MIST analysis, transporter assays etc.) is essential
- Must have cultivated an appropriate attitude to deal with the challenges of drug development and experienced in regulatory interactions
- Experience in a small company environment is highly desirable
- Excellent verbal and written communication skills and willingness to learn and collaborate with other functions of product development & medical development
At Rapport, we believe that one way to advance fairness in compensation is by being transparent. We share our anticipated hiring salary range as part of our commitment to transparency and equity. Our offer will reflect a combination of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, Rapport also offers a generous benefits package. The hiring range for this role is anticipated to be $200,000 to $240,000.
Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
CCPA disclosure notice can be found here.