Are you looking for a role with impact?

Magenta Therapeutics is a clinical-stage biotechnology company developing therapeutics to reset the immune system to cure more patients with devastating and life-threatening diseases. This immune reset approach can be applied through stem cell transplant to multiple diseases, including autoimmune diseases, such as multiple sclerosis and systemic sclerosis; blood cancers, such as acute myeloid leukemia; and genetic diseases, such as sickle cell disease.

Magenta’s comprehensive approach to precision immune system reset will transform many aspects of the transplant process, aiming to make it safer and more effective.  Our culture is fueled by a driven, passionate group of people committed to making a difference, seizing opportunities for maximum impact, and pursuing progress for the patients we seek to serve.

We are seeking a creative clinical and translational medicine expert to develop and execute the clinical development plans for Magenta. This key position with be responsible for evaluating the current Hematopoietic Stem Cell Transplantation landscape and building the strategy for Magenta’s novel drug development programs. The successful candidate will identify and develop relationships with key opinion leaders, patient advocacy groups, academic institutes, and hospitals to integrate novel advances in transplantation research into the drug development process and clinic.

You are perfect for this role if you are engaged by and want to be responsible for:

  • Leading the clinical development strategy and be accountable for the execution of the clinical trials within the company
  • Collaborating closely with our internal research team to integrate translational research into development and clinical strategies
  • Developing and maintaining relationships and serve as the main medical liaison with key opinion leaders and Principal Investigators
  • Leading internal and external team members, vendors, and consultants to develop an IND package, as well as review and evaluate pre-clinical safety data for regulatory submission
  • Being responsible and accountable for the clinical content of all clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, briefing books, CRF’s, annual DSUR reports, CSR’s, ISS’s, ISE’s, and clinical expert reports
  • Organizing and presenting at relevant clinical advisory boards, DMC’s, and medical/scientific meetings
  • Supporting business development processes by providing medical expertise for in- or out-licensing, partnering and acquisition activities
  • Traveling, as needed, nationally and internationally

We would be thrilled if you brought the following with you:

  • MD with research experience or an MD / PhD, with a strong track record in clinical and translational medicine. Specialty training is highly desirable, especially a fellowship in Hematology/ Oncology or related areas
  • Clinical experience in stem cell transplantation within academic medical, pharmaceutical and/or biotechnology sectors is highly desirable
  • Extensive experience in clinical or translational research related to drug development is required: biotech/ pharma experience is required
  • Experience with contributing to regulatory strategy, including experience with IND-enabling, Phase I and Phase II studies preferred
  • Broad therapeutic area and target class expertise and experience in one of the following: Hematology/ Oncology, Auto-immunity and/ or Hematological Rare Genetic Diseases is strongly preferred
  • Ability to identify and build relationships with thought leaders and leading clinical centers
  • Strong academic record with high quality peer-reviewed publications that demonstrate research productivity and the ability to perform cutting edge research in stem cell biology/transplantation, autoimmunity, and/or gene therapy
  • Clear and effective communications (verbal & written) and presentation skills are essential
  • Track record of effective cross-collaboration within an organization, among teams, and external groups/organizations

Successful leaders and contributors within Magenta are: 

  • Driven.  You will be focused on the achievement of Magenta’s mission and major corporate goals.
  • Results-focused.  Demonstrated record of exceeding stretch goals, and willing to bring creative problem-solving skills to challenges along the way
  • Intuitive. You will enjoy learning and being involved in the content of our whole business, thriving on a very fast-paced and growing business
  • Collaborative.  You will have demonstrated the ability to achieve objectives across complex projects and organizational structures
  • Process-oriented, yet flexible. You will appreciate and be able to create and drive process, while also recognizing when flexibility is needed.
  • Transparent and Articulate.  You will have the ability to communicate clearly and concisely with all stakeholders
  • Independent. You will be able to self-organize and operate effectively without significant day-to-day oversight, while staying tightly connected to key leaders and teams across the company
  • A role model for the company’s cultural pillars; Courage Commitment & Excellence


At Magenta, we celebrate our differences. We value the power of a diverse array of folks who bring all of themselves to their work. We embrace cultural, cognitive, social, and professional diversity because we know the only way we’re going to make new cures possible is by working together.

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